Unmasking disease-specific cerebral blood flow abnormalities: mood challenge in patients with remitted unipolar depression

M Liotti, HS Mayberg, S McGinnis… - American Journal of …, 2002 - Am Psychiatric Assoc
OBJECTIVE: Remitted major depressive disorder is a vulnerable clinical state, suggesting
persistence of an underlying disease diathesis between episodes. To investigate neural …

State and trait influences on mood regulation in bipolar disorder: blood flow differences with an acute mood challenge

S Krüger, D Seminowicz, K Goldapple, SH Kennedy… - Biological …, 2003 - Elsevier
BACKGROUND: Even in remission, patients with bipolar disorder (BD) remain sensitive to
external stressors that can trigger new episodes. Imitating such stressors by the controlled …

Increased limbic blood flow and total sleep deprivation in major depression with melancholia

D Ebert, H Feistel, A Barocka, W Kaschka - Psychiatry Research …, 1994 - Elsevier
Single photon emission computed tomography (SPECT) with technetium-99m-d, 1-
hexamethyl-propylene amine oxime (99Tcm-HMPAO) was carried out in 20 melancholic …

The anatomy of melancholia–focal abnormalities of cerebral blood flow in major depression

CJ Bench, KJ Friston, RG Brown, LC Scott… - Psychological …, 1992 - cambridge.org
Using positron emission tomography (PET) and 15Oxygen, regional cerebral blood flow
(rCBF) was measured in 33 patients with primary depression, 10 of whom had an associated …

Regional cerebral blood flow abnormalities in late‐life depression: relation to refractoriness and chronification

S Awata, H Ito, M Konno, S Ono… - Psychiatry and …, 1998 - Wiley Online Library
We examined patterns of regional cerebral blood flow (rCBF) abnormalities in 18 patients
with major depressive disorder in late life using single photon emission computed …

Relationship between regional cerebral blood flow and separate symptom clusters of major depression: a single photon emission computed tomography study using …

CAM Périco, CR Skaf, A Yamada, F Duran… - Neuroscience …, 2005 - Elsevier
This study examined the relationship between resting regional cerebral blood flow (rCBF)
patterns in patients with major depressive disorder (MDD) and specific symptom clusters …

Risk and resilience markers in bipolar disorder: brain responses to emotional challenge in bipolar patients and their healthy siblings

S Krüger, M Alda, LT Young… - American Journal of …, 2006 - Am Psychiatric Assoc
OBJECTIVE: The authors previously identified depression-specific differences in brain
responses to an emotional challenge in patients with bipolar and unipolar mood disorder. In …

Reduction of cerebral blood flow in older depressed patients

IM Lesser, I Mena, KB Boone, BL Miller… - Archives of general …, 1994 - jamanetwork.com
Background: We investigated regional cerebral blood flow in older, drug-free depressed
patients and examined factors that might be related to rCBF. Methods: We studied 39 …

State-dependent differences in emotion regulation between unmedicated bipolar disorder and major depressive disorder

MM Rive, RJT Mocking, MWJ Koeter… - JAMA …, 2015 - jamanetwork.com
Importance Major depressive disorder (MDD) and bipolar disorder (BD) are difficult to
distinguish clinically during the depressed or remitted states. Both mood disorders are …

Baseline brain perfusion and brain structure in patients with major depression: a multimodal magnetic resonance imaging study

N Vasic, ND Wolf, G Grön, Z Sosic-Vasic… - Journal of Psychiatry and …, 2015 - jpn.ca
Background: Abnormal regional cerebral blood flow (rCBF) and grey matter volume have
been frequently reported in patients with major depressive disorder (MDD). However, it is …