Ipconazole disrupts mitochondrial homeostasis and alters GABAergic neuronal development in zebrafish

G Lee, A Banik, J Eum, BJ Hwang, SH Kwon… - International Journal of …, 2022 - mdpi.com
Ipconazole, a demethylation inhibitor of fungal ergosterol biosynthesis, is widely used in
modern agriculture for foliar and seed treatment, and is authorized for use in livestock feed …

Sub-lethal effects of the triazole fungicide propiconazole on zebrafish (Danio rerio) development, oxidative respiration, and larval locomotor activity

CL Souders II, P Xavier, V Perez-Rodriguez… - Neurotoxicology and …, 2019 - Elsevier
Propiconazole is a triazole fungicide used in agriculture. Via run-off, it can enter the aquatic
environment, and can adversely affect organisms. However, data are scarce on how …

A comprehensive review of 1, 2, 4-triazole fungicide toxicity in zebrafish (Danio rerio): A mitochondrial and metabolic perspective

T Huang, H Jiang, Y Zhao, J He, H Cheng… - Science of The Total …, 2022 - Elsevier
In this critical review, we synthesize data from peer-reviewed literature reporting on triazole
fungicide exposures in the zebrafish model. Based on their mode of action in plants (potent …

Embryonic toxicity of epoxiconazole exposure to the early life stage of zebrafish

Y Weng, Z Huang, A Wu, Q Yu, H Lu, Z Lou, L Lu… - Science of The Total …, 2021 - Elsevier
Epoxiconazole (EPX), as a broad-spectrum triazole fungicide, is widely used in agriculture to
resist pests and diseases, while it may have potential toxicity to non-target organisms. In the …

Transcriptome analysis reveals benzotriazole ultraviolet stabilizers regulate networks related to inflammation in juvenile zebrafish (Danio rerio) brain

Z Li, W Li, J Zha, H Chen, CJ Martyniuk… - Environmental …, 2019 - Wiley Online Library
Benzotriazole ultraviolet stabilizers (BUVSs) are widely applied ultraviolet absorbing
compounds in industrial materials and personal care products. Due to their ubiquitous use …

Oxamyl exerts developmental toxic effects in zebrafish by disrupting the mitochondrial electron transport chain and modulating PI3K/Akt and p38 Mapk signaling

G An, T Hong, H Park, W Lim, G Song - Science of The Total Environment, 2023 - Elsevier
Oxamyl, a carbamate insecticide, is mainly used to control nematodes in the agricultural
field. Although oxamyl is a widely used insecticide that is associated with ecological …

Hexaconazole induces developmental toxicities via apoptosis, inflammation, and alterations of Akt and MAPK signaling cascades

H Lee, W Park, G An, J Park, W Lim, G Song - … Biochemistry and Physiology …, 2024 - Elsevier
Hexaconazole is a highly effective triazole fungicide that is frequently applied in various
countries to elevate crop productivity. Given its long half-life and high water solubility, this …

Epoxiconazole altered hepatic metabolism in adult zebrafish based on transcriptomic analysis

Y Weng, W Gu, Y Jin - Comparative Biochemistry and Physiology Part C …, 2024 - Elsevier
Epoxiconazole (EPX) is a triazole fungicide, which has been widely used in pest control of
cereal crops. However, its extensive use has led to concerning levels of residue in water …

Developmental toxicity of procymidone to larval zebrafish based on physiological and transcriptomic analysis

A Wu, Q Yu, H Lu, Z Lou, Y Zhao, T Luo, Z Fu… - … and Physiology Part C …, 2021 - Elsevier
As a broad-spectrum with low toxicity, procymidone (PCM), is widely used in agriculture and
frequently observed in aquatic system, which may cause some impacts on aquatic …

Aclonifen causes developmental abnormalities in zebrafish embryos through mitochondrial dysfunction and oxidative stress

JY Lee, H Park, W Lim, G Song - Science of The Total Environment, 2021 - Elsevier
The herbicide aclonifen is commonly used in agriculture. Aclonifen is toxic to experimental
animals, causing developmental abnormalities, decreased energy production for survival …