Sex differences in anxiety and depression: circuits and mechanisms

DA Bangasser, A Cuarenta - Nature Reviews Neuroscience, 2021 - nature.com
Epidemiological sex differences in anxiety disorders and major depression are well
characterized. Yet the circuits and mechanisms that contribute to these differences are …

[HTML][HTML] Sex differences in stress response: classical mechanisms and beyond

GE Hodes, D Bangasser, I Sotiropoulos… - Current …, 2023 - ncbi.nlm.nih.gov
Neuropsychiatric disorders, which are associated with stress hormone dysregulation, occur
at different rates in men and women. Moreover, nowadays, preclinical and clinical evidence …

Sex differences and the neurobiology of affective disorders

DR Rubinow, PJ Schmidt - Neuropsychopharmacology, 2019 - nature.com
Observations of the disproportionate incidence of depression in women compared with men
have long preceded the recent explosion of interest in sex differences. Nonetheless, the …

[HTML][HTML] Sex differences in mood disorders: perspectives from humans and rodent models

ML Seney, E Sibille - Biology of sex differences, 2014 - Springer
Mood disorders are devastating, often chronic illnesses characterized by low mood, poor
affect, and anhedonia. Notably, mood disorders are approximately twice as prevalent in …

Sex‐specific mechanisms for responding to stress

DA Bangasser, B Wicks - Journal of neuroscience research, 2017 - Wiley Online Library
Posttraumatic stress disorder and major depression share stress as an etiological
contributor and are more common in women than in men. Traditionally, preclinical studies …

What do we know about sex differences in depression: A review of animal models and potential mechanisms

L Ma, Y Xu, G Wang, R Li - Progress in Neuro-Psychopharmacology and …, 2019 - Elsevier
Clinical studies have shown that women are more susceptible to depression than men. Sex
differences in depression have been associated with social, cultural, as well as biological …

Sex differences in depression and anxiety

P Pavlidi, N Kokras, C Dalla - Sex Differences in Brain Function and …, 2022 - Springer
Depression and anxiety disorders carry a tremendous worldwide burden and emerge as a
significant cause of disability among western societies. Both disorders are known to …

Sex differences: Transcriptional signatures of stress exposure in male and female brains

E Brivio, JP Lopez, A Chen - Genes, brain and behavior, 2020 - Wiley Online Library
More than two‐thirds of patients suffering from stress‐related disorders are women but over
two‐thirds of suicide completers are men. These are just some examples of the many sex …

Preclinical sex differences in depression and antidepressant response: Implications for clinical research

N Kokras, C Dalla - Journal of neuroscience research, 2017 - Wiley Online Library
Women suffer from depression and anxiety disorders more often than men, and as a result
they receive antidepressants to a greater extent. Sex differences in antidepressant response …

Genetic and epigenetic factors underlying sex differences in the regulation of gene expression in the brain

VS Ratnu, MR Emami, TW Bredy - Journal of neuroscience …, 2017 - Wiley Online Library
There are inherent biological differences between males and females that contribute to sex
differences in brain function and to many sex‐specific illnesses and disorders. Traditionally …