[HTML][HTML] Biomarkers of aging in frailty and age-associated disorders: State of the art and future perspective

S Salvioli, MS Basile, L Bencivenga, S Carrino… - Ageing Research …, 2023 - Elsevier
According to the Geroscience concept that organismal aging and age-associated diseases
share the same basic molecular mechanisms, the identification of biomarkers of age that can …

[HTML][HTML] Frailty in aging and the search for the optimal biomarker: a review

M Sepúlveda, D Arauna, F García, C Albala, I Palomo… - Biomedicines, 2022 - mdpi.com
In the context of accelerated aging of the population worldwide, frailty has emerged as one
of the main risk factors that can lead to loss of self-sufficiency in older people. This syndrome …

[HTML][HTML] Biomarkers of Aging and Relevant Evaluation Techniques: A Comprehensive Review

X Tao, Z Zhu, L Wang, C Li, L Sun, W Wang… - Aging and …, 2024 - ncbi.nlm.nih.gov
The risk of developing chronic illnesses and disabilities is increasing with age. To predict
and prevent aging, biomarkers relevant to the aging process must be identified. This paper …

Aging biomarkers: from functional tests to multi‐omics approaches

KS Kudryashova, K Burka, AY Kulaga… - …, 2020 - Wiley Online Library
Aging results in various deleterious changes in the human body that may lead to loss of
function and the manifestation of chronic diseases. While diseases can generally be reliably …

The shift of the paradigm between ageing and diseases

F Salvatore - Clinical Chemistry and Laboratory Medicine (CCLM), 2020 - degruyter.com
In the area of the Medical Sciences, the chronological age has always been, and still is, an
indicator by which we try to understand the health status of an individual. However, besides …

An evaluation of aging measures: from biomarkers to clocks

Q Wang, T Hou, Q Wang, J He, L Wang, J Si, S Chen - Biogerontology, 2023 - Springer
With the increasing number of aged population and growing burden of healthy aging
demands, a rational standard for evaluation aging is in urgent need. The advancement of …

Potential biomarkers of ageing

A Simm, N Nass, B Bartling, B Hofmann, RE Silber… - 2008 - degruyter.com
Life span in individual humans is very heterogeneous. Thus, the ageing rate, measured as
the decline of functional capacity and stress resistance, is different in every individual. There …

Frailty biomarkers under the perspective of geroscience: a narrative review

RSSA Gonçalves, ÁCC Maciel, Y Rolland… - Ageing research …, 2022 - Elsevier
Cellular and molecular aging biomarkers might contribute to identify at-risk individuals for
frailty before overt clinical manifestations appear. Although studies on the associations of …

[HTML][HTML] Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases

AL Cardoso, A Fernandes, JA Aguilar-Pimentel… - Ageing research …, 2018 - Elsevier
Objective Use of the frailty index to measure an accumulation of deficits has been proven a
valuable method for identifying elderly people at risk for increased vulnerability, disease …

Biomarkers of aging

X Bai - Aging and Aging-Related Diseases: Mechanisms and …, 2018 - Springer
Biomarkers of aging are a biological parameter that can predict the functional status of an
individual in the absence of disease and can be used to better predict morbidity and …