[HTML][HTML] Microvascular and macrovascular complications of type 2 diabetes mellitus: Exome wide association analyses

A Mansour, M Mousa, D Abdelmannan, G Tay… - Frontiers in …, 2023 - frontiersin.org
Background Type 2 diabetes mellitus (T2DM) is a chronic, metabolic disorder in which
concomitant insulin resistance and β-cell impairment lead to hyperglycemia, influenced by …

[HTML][HTML] Genetic variants and their associations to type 2 diabetes mellitus complications in The United Arab Emirates

S ElHajj Chehadeh, NS Sayed… - Frontiers in …, 2022 - frontiersin.org
Aim Type 2 Diabetes Mellitus (T2DM) is associated with microvascular complications,
including diabetic retinopathy (DR), diabetic nephropathy (DNp), and diabetic peripheral …

[HTML][HTML] The first exome wide association study in Tunisia: identification of candidate loci and pathways with biological relevance for type 2 diabetes

H Dallali, W Boukhalfa, N Kheriji, M Fassatoui… - Frontiers in …, 2023 - frontiersin.org
Introduction Type 2 diabetes (T2D) is a multifactorial disease involving genetic and
environmental components. Several genome-wide association studies (GWAS) have been …

Genetic risk factors for type 2 diabetes: insights from the emerging genomic evidence

EE Ntzani, FK Kavvoura - Current Vascular Pharmacology, 2012 - ingentaconnect.com
Type-2 diabetes is a complex disease modified by a number of environmental and genetic
factors that contribute at varying degrees to the final phenotype and possibly interact with …

[HTML][HTML] Genome-wide association study of type 2 diabetes in Africa

J Chen, M Sun, A Adeyemo, F Pirie, T Carstensen… - Diabetologia, 2019 - Springer
Aims/hypothesis Genome-wide association studies (GWAS) for type 2 diabetes have
uncovered> 400 risk loci, primarily in populations of European and Asian ancestry. Here, we …

[HTML][HTML] Novel susceptibility loci identified in a genome-wide association study of type 2 diabetes complications in population of Latvia

M Ustinova, R Peculis, R Rescenko, V Rovite… - BMC Medical …, 2021 - Springer
Background Type 2 diabetes complications cause a serious emotional and economical
burden to patients and healthcare systems globally. Management of both acute and chronic …

[HTML][HTML] Genetic studies on diabetic microvascular complications: focusing on genome-wide association studies

SH Kwak, KS Park - Endocrinology and metabolism, 2015 - ncbi.nlm.nih.gov
Diabetes is a common metabolic disorder with a worldwide prevalence of 8.3% and is the
leading cause of visual loss, end-stage renal disease and amputation. Recently, genome …

[HTML][HTML] Identification of genes and signaling pathways associated with diabetic neuropathy using a weighted correlation network analysis: A consort study

Y Li, W Ma, C Xie, M Zhang, X Yin, F Wang, J Xu, B Shi - Medicine, 2016 - journals.lww.com
Background: The molecular mechanisms behind diabetic neuropathy remains to be
investigated. Methods: This is a secondary study on microarray dataset (GSE24290) …

[HTML][HTML] Evaluation of genome wide association study associated type 2 diabetes susceptibility loci in sub Saharan Africans

AA Adeyemo, F Tekola-Ayele, AP Doumatey… - Frontiers in …, 2015 - frontiersin.org
Genome wide association studies (GWAS) for type 2 diabetes (T2D) undertaken in
European and Asian ancestry populations have yielded dozens of robustly associated loci …

[HTML][HTML] T2DiACoD: a gene atlas of type 2 diabetes mellitus associated complex disorders

J Rani, I Mittal, A Pramanik, N Singh, N Dube… - Scientific reports, 2017 - nature.com
We performed integrative analysis of genes associated with type 2 Diabetes Mellitus (T2DM)
associated complications by automated text mining with manual curation and also gene …