Cancer is a multi-scale disease and its overwhelming complexity depends upon the multiple
interwind events occurring at both molecular and cellular levels, making it very difficult for …

Cancer is a major global health problem and a leading cause of deaths worldwide [6].
According to the International Agency for Research on Cancer, there were 12.7 million new …

There are several standard modalities of cancer therapy, among which chemotherapy is the
most commonly employed. Drugs used in chemotherapy could reduce the tumour mass or …

Diverse forms of resistance to anticancer drugs can lead to the failure of chemotherapy.
Drug resistance is one of the most intractable issues for successfully treating cancer in …

Recent data have demonstrated that cancer drug resistance reflects complex biologic
factors, including tumor heterogeneity, varying growth, differentiation, apoptosis pathways …

Abstract Purpose of Review Successful, durable cancer treatment is limited by drug
resistance. Cancer stem cells (CSC) comprise (typically) a rare tumor subpopulation that …

This document can be treated as Final Thesis Report for the project titled” Multi-Drug
Resistance on Cancer Cell Lines”. Drug is said to be resistant on cancer site if it doesn't bind …

Background Drug-induced resistance is one the major obstacles that may lead to
therapeutic failure during cancer treatment. Different genetic alterations occur when tumor …

Although targeted therapy is yielding promising results in the treatment of specific cancers,
drug resistance poses a problem. We develop a mathematical framework that can be used …

The most challenging task in colorectal cancer research nowadays is to understand the
development of acquired resistance to anti-EGFR drugs. The key reason for this problem is …