Molecular biology of atherosclerosis

PN Hopkins - Physiological reviews, 2013 - journals.physiology.org
At least 468 individual genes have been manipulated by molecular methods to study their
effects on the initiation, promotion, and progression of atherosclerosis. Most clinicians and …

Atherosclerosis pathophysiology and the role of novel risk factors: a clinicobiochemical perspective

V Mallika, B Goswami, M Rajappa - Angiology, 2007 - journals.sagepub.com
Atherosclerosis is the root cause of the biggest killer of the 21st century. Mechanisms
contributing to atherogenesis are multiple and complex. A number of theories—including the …

[图书][B] Atherosclerosis: molecular and cellular mechanisms

SJ George, J Johnson - 2010 - books.google.com
With atherosclerosis being the number one cause of death in the western world, this
handbook and ready reference provides a comprehensive account of the different stages …

Gene expression phenotypes of atherosclerosis

D Seo, T Wang, H Dressman, EE Herderick… - … , and vascular biology, 2004 - Am Heart Assoc
Objective—Fulfilling the promise of personalized medicine by developing individualized
diagnostic and therapeutic strategies for atherosclerosis will depend on a detailed …

Atherosclerosis: successes, surprises, and future challenges

P Libby, KE Bornfeldt, AR Tall - Circulation research, 2016 - Am Heart Assoc
532 Circulation Research February 19, 2016 unresolved questions and to exploit the newer
discoveries that have opened unanticipated horizons of understanding and raised novel …

Vascular biology of atherosclerosis: overview and state of the art

P Libby - The American journal of cardiology, 2003 - Elsevier
Our current understanding of the vascular biology of atherogenesis and its clinical
manifestations suggests a pathophysiology that is much more complex than mere lipid …

Molecular and cellular concepts in atherosclerosis

M Sanders - Pharmacology & therapeutics, 1994 - Elsevier
Atherosclerosis is a complex disease of uncertain cause. Its pathobiology is believed to
represent an abnormal expression of the processes of vascular healing. Etiologic models …

The biology of atherosclerosis comes full circle: lessons for conquering cardiovascular disease

P Libby - Nature Reviews Cardiology, 2021 - nature.com
Atherosclerosis causes myocardial infarction, ischaemic cardiomyopathy, many ischaemic
strokes and jeopardized limbs. Despite enormous progress, atherosclerosis has become the …

Pathophysiology of cardiovascular diseases: new insights into molecular mechanisms of atherosclerosis, arterial hypertension, and coronary artery disease

W Frąk, A Wojtasińska, W Lisińska, E Młynarska… - Biomedicines, 2022 - mdpi.com
Cardiovascular diseases (CVDs) are disorders associated with the heart and circulatory
system. Atherosclerosis is its major underlying cause. CVDs are chronic and can remain …

Pathobiology of atherosclerosis-a brief review

N Kher, JD Marsh - Seminars in thrombosis and hemostasis, 2004 - thieme-connect.com
Considerable progress has been made recently in understanding the pathobiology of
atherosclerosis. To a significant degree it is an inflammatory disease of the vessel wall …