Background Schizophrenia commonly co-occurs with cardiometabolic and inflammation-
related traits. It is unclear to what extent the comorbidity could be explained by shared …

Objective: Schizophrenia is associated with increased risk of cardiovascular disease (CVD),
although there is variation in risk among individuals. There are indications of shared genetic …

Individuals with schizophrenia (SCZ) have, on average, a 10-to 20-year shorter expected life
span than the rest of the population, primarily due to cardiovascular disease comorbidity …

Genome-wide association studies (GWAS) have identified abundant risk loci associated with
schizophrenia (SCZ), cardiometabolic disease (CMD) including body mass index, coronary …

BackgroundCardiovascular diseases represent a major health issue in patients with
schizophrenia (SCZ) and bipolar disorder (BD), but the exact nature of cardiometabolic (CM) …

Here, we used data from large genome-wide association studies to test the presence of
causal relationships, conducting a Mendelian randomization analysis; and shared molecular …

Individuals with schizophrenia have a reduced life-expectancy compared to the general
population, largely due to an increased risk of cardiovascular disease (CVD). Clinical and …

Aim The genetic relationship between schizophrenia (SCZ) and other nonpsychiatric
disorders remains largely unknown. We examined the shared genetic components between …

Background Insulin resistance predisposes to cardiometabolic disorders, which are
commonly comorbid with schizophrenia and are key contributors to the significant excess …

Several lines of evidence suggest that genome-wide association studies (GWASs) have the
potential to explain more of the" missing heritability" of common complex phenotypes …