Mediators of the initiation, development, and recurrence of periodontitis include the oral
microbiome embedded in subgingival plaque and the host immune response to a dysbiosis …

The landscape in dentistry is changing as emerging studies continue to reveal that
periodontal health impacts systemic health, and vice versa. Population studies, clinical …

The human oral cavity is home to a large and diverse community of viruses that have yet to
be characterized in patients with periodontal disease. We recruited and sampled saliva and …

Seminal studies published in the 1990s and 2000s explored connections between
periodontal diseases and systemic conditions, revealing potential contributions of …

Human cytomegalovirus and Epstein‐Barr virus type 1 are discussed in this review as they
relate to destructive periodontal disease in humans. Genomes of the two herpesviruses …

Periodontitis is one of the most complex infectious diseases of the human body. Individual
periodontal lesions may harbor millions of genomic copies of herpesviruses (179) as well as …

Recent advances in our understanding of the microbial populations that colonize the human
mouth, their acquisition, interdependency, and coevolution with the host, bring a different …

Periodontitis is an infectious/inflammatory disease characterized by the loss of periodontal
ligament and alveolar bone. Herpesviruses are frequent inhabitants of periodontitis lesions …

Recent studies have identified various herpesviruses in human periodontal disease. Epstein–
Barr virus type 1 (EBV‐1) infects periodontal B‐lymphocytes and human cytomegalovirus …

The significance of microbiology and immunology with regard to caries and periodontal
disease gained substantial clinical or research consideration in the mid 1960's. This …