Vaccines against parasites have lagged centuries behind those against viral and bacterial
infections, despite the devastating morbidity and widespread effects of parasitic diseases …

Traditional vaccine technologies have resulted in an impressive array of efficacious
vaccines against a variety of infectious agents. However, several potentially deadly …

Protection against malaria through vaccination is known to be achievable, as first
demonstrated over 30 years ago. Vaccination via repeated bites with Plasmodium …

Viral vectors have been developed as vaccine platforms for a number of pathogens and
tumors. In particular, adenovirus (Ad)-based vectors expressing genes coding for pathogen …

Adenoviral vectors are a safe and potently immunogenic vaccine delivery platform. Non-
replicating Ad vectors possess several attributes which make them attractive vaccines for …

Vaccination is one of the most efficient tools for disease prevention, and a continuously
growing field of research. However, despite progress, we still need more efficient and cost …

Several human adenoviral (Ad) vectors have been developed for vaccine delivery owing to
their numerous advantages, including the feasibility of different vector designs, the …

An ideal malaria vaccine platform should potently induce protective immune responses and
block parasite transmission from mosquito to human, and it should maintain these effects for …

An adenoviral (AdV)-based vector system is a promising platform for vaccine development
and gene therapy applications. Administration of an AdV vector elicits robust innate …

Adenoviral vectored vaccines against infectious diseases are currently in clinical trials due
to their capacity to induce potent antigen-specific B-and T-cell immune responses …