Epigenetic inheritance of polycystic ovary syndrome—challenges and opportunities for treatment

E Stener-Victorin, Q Deng - Nature Reviews Endocrinology, 2021 - nature.com
Polycystic ovary syndrome (PCOS) is the main cause of female infertility worldwide and is
associated with a substantially increased lifetime risk of comorbidities, including type 2 …

Genetic basis of polycystic ovary syndrome (PCOS): current perspectives

MJ Khan, A Ullah, S Basit - The application of clinical genetics, 2019 - Taylor & Francis
Polycystic ovary syndrome (PCOS) is a common infertility disorder affecting a significant
proportion of the global population. It is the main cause of anovulatory infertility in women …

The genetics of the polycystic ovary syndrome

M Urbanek - Nature clinical practice Endocrinology & metabolism, 2007 - nature.com
Polycystic ovary syndrome (PCOS) is a very common endocrine disorder that has a strong
genetic component and is characterized by polycystic ovaries, hyperandrogenemia, and …

[图书][B] Polycystic ovary syndrome: current controversies, from the ovary to the pancreas

A Dunaif, RJ Chang, S Franks, RS Legro - 2008 - books.google.com
All four editors of this title are extremely prominent in the field of PCOS. Although they are all
US-based, they are internationally renowned. The book includes the latest diagnostic criteria …

Genetics of polycystic ovary syndrome

TM Barber, S Franks - Polycystic ovary syndrome, 2013 - karger.com
Polycystic ovary syndrome (PCOS) is an oligogenic condition, with a heritability of∼ 70%.
PCOS is also associated with obesity, which itself is heavily influenced by genetic variants …

The role of genes in the polycystic ovary syndrome: predisposition and mechanisms

E Deligeoroglou, C Kouskouti… - Gynecological …, 2009 - Taylor & Francis
The polycystic ovary syndrome (PCOS), mainly characterized by clinical and/or biochemical
hyperandrogenism, ovarian dysfunction and/or polycystic morphology as well as associated …

Polycystic ovary syndrome: the epigenetics behind the disease

MC Eiras, DP Pinheiro, KAM Romcy, RA Ferriani… - Reproductive …, 2022 - Springer
Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders,
affecting approximately 5–20% of women of reproductive age. PCOS is a multifactorial …

Genetics of polycystic ovary syndrome

K Mykhalchenko, D Lizneva, T Trofimova… - Expert review of …, 2017 - Taylor & Francis
Introduction: Polycystic ovary syndrome (PCOS) is a hormonal and metabolic disorder
affecting 5 to 20% of reproductive-aged women worldwide that results in androgen excess …

Hyperandrogenic origins of polycystic ovary syndrome–implications for pathophysiology and therapy

DH Abbott, DA Dumesic, JE Levine - Expert review of …, 2019 - Taylor & Francis
Introduction: Polycystic ovary syndrome (PCOS) diagnosis comprises combinations of
female hyperandrogenism, menstrual irregularity and polycystic ovaries. While it is a familial …

New insights into the genetics of polycystic ovary syndrome

R Azziz - Nature Reviews Endocrinology, 2016 - nature.com
In 2015, large-scale genetic and functional studies brought us closer to understanding the
underlying aetiology of polycystic ovary syndrome (PCOS), implicating genes involved in …