Xuanfei Baidu Decoction reduces acute lung injury by regulating infiltration of neutrophils and macrophages via PD-1/IL17A pathway

Y Wang, X Wang, Y Li, Z Xue, R Shao, L Li, Y Zhu… - Pharmacological …, 2022 - Elsevier
The pathogenic hyper-inflammatory response has been revealed as the major cause of the
severity and death of the Corona Virus Disease 2019 (COVID-19). Xuanfei Baidu Decoction …

Traditional Chinese Medicine, Qingfei Paidu Decoction and Xuanfei Baidu Decoction, Inhibited Cytokine Production via NF-κB Signaling Pathway in Macrophages …

Y Li, B Li, P Wang, Q Wang - Frontiers in Pharmacology, 2021 - frontiersin.org
Background and Aims: Qingfei Paidu decoction (QPD) and Xuanfei Baidu decoction (XBD)
are two typical traditional Chinese medicines with proven efficacy for the treatment of SARS …

Xuanfei Baidu Decoction protects against macrophages induced inflammation and pulmonary fibrosis via inhibiting IL-6/STAT3 signaling pathway

Y Wang, X Sang, R Shao, H Qin, X Chen, Z Xue… - Journal of …, 2022 - Elsevier
Abstract Ethnopharmacological relevance Xuanfei Baidu Decoction (XFBD), one of the
“three medicines and three prescriptions” for the clinically effective treatment of COVID-19 in …

[HTML][HTML] Xuanfei Baidu formula alleviates impaired mitochondrial dynamics and activated NLRP3 inflammasome by repressing NF-κB and MAPK pathways in LPS …

Z Li, H Pan, J Yang, D Chen, Y Wang, H Zhang… - Phytomedicine, 2023 - Elsevier
Abstract Background Xuanfei Baidu Formula (XBF) is an effective traditional Chinese
medicine (TCM) remedy for treating coronavirus disease 2019 (COVID-19) in China. This …

Re-Du-Ning injection ameliorates LPS-induced lung injury through inhibiting neutrophil extracellular traps formation

C Yang, C Song, Y Liu, J Qu, H Li, W Xiao, L Kong… - Phytomedicine, 2021 - Elsevier
Background Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are life-
threatening diseases and could occur in severe COVID-19 patients. Re-Du-Ning injection …

Dachengqi decoction alleviates acute lung injury and inhibits inflammatory cytokines production through TLR4/NF‐κB signaling pathway in vivo and in vitro

XX Hu, S Liu, J Zhu, HB Ni - Journal of cellular biochemistry, 2019 - Wiley Online Library
Abstract Background and Objectives Sepsis that arises from uncontrolled pulmonary
inflammation could induce acute lung injury (ALI), leading to the high death rate. Dachengqi …

Chemical composition and pharmacological mechanism of Qingfei Paidu Decoction and Ma Xing Shi Gan Decoction against Coronavirus Disease 2019 (COVID-19) …

R Yang, H Liu, C Bai, Y Wang, X Zhang, R Guo… - Pharmacological …, 2020 - Elsevier
Abstract The Coronavirus Disease 2019 (COVID-19) pandemic has become a huge threaten
to global health, which raise urgent demand of developing efficient therapeutic strategy. The …

Xuanfei Baidu decoction attenuates intestinal disorders by modulating NF-κB pathway, regulating T cell immunity and improving intestinal flora

L Ma, X Zhao, T Liu, Y Wang, J Wang, L Kong, Q Zhao… - Phytomedicine, 2022 - Elsevier
Background A number of studies have shown that gastrointestinal manifestations co-exist
with respiratory symptoms in coronavirus disease 2019 (COVID-19) patients. Xuanfei Baidu …

Systems pharmacological study illustrates the immune regulation, anti-infection, anti-inflammation, and multi-organ protection mechanism of Qing-Fei-Pai-Du …

J Zhao, S Tian, D Lu, J Yang, H Zeng, F Zhang, D Tu… - Phytomedicine, 2021 - Elsevier
Abstract Background The traditional Chinese medicine (TCM) formula Qing-Fei-Pai-Du
decoction (QFPDD) was the most widely used prescription in China's campaign to contain …

Dexmedetomidine ameliorates LPS induced acute lung injury via GSK-3β/STAT3-NF-κB signaling pathway in rats

H Zhang, J Sha, X Feng, X Hu, Y Chen, B Li… - International …, 2019 - Elsevier
Acute lung injury (ALI) is a serious complication of sepsis and an important cause of death in
intensive care. Studies have shown that DEX can inhibit inflammation. However, the anti …