Chaperone-usher fimbrial adhesins are powerful weapons against the uropathogens that
allow the establishment of urinary tract infections (UTIs). As the antibiotic therapeutic …

The initial step for the successful establishment of urinary tract infections (UTIs),
predominantly caused by uropathogenic Escherichia coli, is the adhesion of bacteria to …

Urinary tract infections (UTIs) are caused primarily by uropathogenic Escherichia coli
(UPEC), which encode filamentous surface‐adhesive organelles called type 1 pili. FimH is …

ABSTRACT Introduction: The bacterial adhesin FimH is a virulence factor and an attractive
therapeutic target for urinary tract infection (UTI) and Crohn's Disease (CD). Located on type …

Background Escherichia coli strains adhere to the normally sterile human uroepithelium
using type 1 pili, that are long, hairy surface organelles exposing a mannose-binding FimH …

Urinary tract infections (UTIs), predominantly caused by uropathogenic Escherichia coli
(UPEC), belong to the most prevalent infectious diseases worldwide. The attachment of …

Uropathogenic Escherichia coli (UPEC) are the major causative agents of urinary tract
infections. During infection, UPEC adhere to mannosylated glycoreceptors on the urothelium …

FimH-mediated cellular adhesion to mannosylated proteins is critical in the ability of
uropathogenic E. coli (UPEC) to colonize and invade the bladder epithelium during urinary …

Multivalent carbohydrate–lectin interactions at host–pathogen interfaces play a crucial role
in the establishment of infections. Although competitive antagonists that prevent pathogen …

Introduction: Type 1 pili are utilized by Gram-negative bacteria to adhere to host tissue and
thus are a key virulence factor in urinary tract infections (UTIs) and Crohn's disease (CD) …