Publisher Summary This chapter discusses the principles governing the integrins, their
capacity to recognize ligands, cellular regulation of integrin function, and aspects of integrin …

It has been well established that integrins mediate cell–cell and cell–matrix adhesion and
play crucial roles in the immune system such as leukocyte–endothelium interactions …

Publisher Summary A family of cell adhesion receptors, termed integrins, has been defined
that potentiate a wide variety of cell-cell and cell-matrix interactions. Integrins not only …

Adhesive interactions are crucial for the integrity and function of all cells and tissues. As one
of the major families of cell adhesion receptors, the integrins have been the focus of …

Coordinated cell-cell and cell-substratum interactions are crucial for the differentiation.
organization and diverse somatic functions of multicellular organisms. Several families of …

Cell communication is essential to development, tissue organization and function of all
multicellular organisms. Cells communicate with each other and with their environment via …

Integrins are heterodimeric cell adhesion molecules that link the extracellular matrix to the
cytoskeleton. The integrin family in man comprises 24 members, which are the result of …

Integrins participate in many aspects of immunologic and inflammatory responses,
especially those involving cell migration, adherence, and activation. Although leukocyte …

Adhesion is a crucial requirement for the correct regulation of immune and inflammatory
responses. In the immune system, leukocytes can interact with each other and with vascular …

Integrins: Molecular and Biological Responses to the Extracellular Matrix will help basic,
applied, and clinical researchers keep up with the explosion of literature on the integrin …