AA Riccio, ED Sullivan, WC Copeland - Journal of Biological Chemistry, 2022 - ASBMB
Understanding the core replication complex of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is essential to the development of novel coronavirus-specific …
M Saramago, VG Costa, CS Souza, C Bárria… - Microorganisms, 2022 - mdpi.com
The pandemic caused by SARS-CoV-2 is not over yet, despite all the efforts from the scientific community. Vaccination is a crucial weapon to fight this virus; however, we still …
NS Ogando, JC Zevenhoven-Dobbe… - Journal of …, 2020 - Am Soc Microbiol
Coronaviruses (CoVs) stand out for their large RNA genome and complex RNA-synthesizing machinery comprising 16 nonstructural proteins (nsps). The bifunctional nsp14 contains 3 …
X Bai, H Sun, S Wu, Y Li, L Wang, B Hong - Frontiers in Immunology, 2022 - frontiersin.org
SARS-CoV-2 (severe acute respiratory syndrome coronavirus‐2), a member of the coronavirus family, appeared in 2019 and has caused the largest global public health and …
J Zeng, F Weissmann, AP Bertolin, V Posse… - Biochemical …, 2021 - portlandpress.com
The coronavirus disease 2019 (COVID-19) pandemic, which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a global public health challenge …
CT Lim, KW Tan, M Wu, R Ulferts… - Biochemical …, 2021 - portlandpress.com
The COVID-19 pandemic has emerged as the biggest life-threatening disease of this century. Whilst vaccination should provide a long-term solution, this is pitted against the …
S Lin, H Chen, Z Chen, F Yang, F Ye… - Nucleic acids …, 2021 - academic.oup.com
The emergence of SARS-CoV-2 infection has posed unprecedented threat to global public health. The virus-encoded non-structural protein 14 (nsp14) is a bi-functional enzyme …
AP Bertolin, F Weissmann, J Zeng, V Posse… - Biochemical …, 2021 - portlandpress.com
The coronavirus disease 2019 (COVID-19) global pandemic has turned into the largest public health and economic crisis in recent history impacting virtually all sectors of society …
N Narayanan, DT Nair - International Journal of Biological Macromolecules, 2021 - Elsevier
SARS-CoV-2is the causative agent for the ongoing COVID19 pandemic, and this virus belongs to the Coronaviridae family. The nsp14 protein of SARS-CoV-2 houses a 3′ to 5 …