Chitosan is widely used in the biomedical field due its chemical and pharmacological
properties. However, intake of chitosan results in renal tissue accumulation of chitosan and …

Urine pH has been thought to be an important factor that can modulate kidney stone
formation. Nevertheless, there was no systematic evaluation of such pH effect. Our present …

We investigated the effects of a traditional Chinese herbal formula, Wulingsan (WLS), on
renal stone prevention using an ethylene glycol-induced nephrocalcinosis rat model. Forty …

Formation of calcium oxalate stones tends to increase with age and begins from the
attachment of a crystal formed in the cavity of renal tubules to the surface of renal tubular …

The establishment of an experimental animal model would be useful to study the
mechanism of kidney stone formation. A calcium kidney stone model in rats induced by …

Background: Although nephrotoxic in high doses, ethylene glycol (EG) has been used with
ammonium chloride (NH4Cl) or vitamin D3 to study calcium oxalate stone formation in rat …

Dietary oxalate is plant-derived and may be a component of vegetables, nuts, fruits, and
grains. In normal individuals, approximately half of urinary oxalate is derived from the diet …

Kidney stone disease is one of the oldest diseases known to medicine; however, the
mechanisms of stone formation and development remain largely unclear. Over the past …

Citrate inhibits growth of residual fragments in an in vitro model of calcium oxalate renal
stones. Background Alkaline citrate is thought to be helpful in reducing recurrences of …

The role of dietary oxalate in calcium oxalate kidney stone formation remains unclear.
However, due to the risk for stone disease that is associated with a low calcium intake …