Peritoneal dialysis (PD) is limited by chronic fibrotic remodeling of the peritoneal wall, a
transforming growth factor-β (TGF-β)-mediated process. The fractalkine (CX3CL1) receptor …

Peritoneal fibrosis (PF) is an irreversible complication of peritoneal dialysis (PD) that leads
to loss of peritoneal membrane function. We investigated PD effluent and serum levels and …

The inhibition of several chemokine/chemokine receptors has been shown to reduce
progressive renal interstitial fibrosis. In this study, we examined the expression of the CX 3 C …

Peritoneal fibrosis remains a problem in kidney failure patients treated with peritoneal
dialysis. Severe peritoneal fibrosis with encapsulation or encapsulating peritoneal sclerosis …

Hypertension promotes and escalates kidney injury, including kidney fibrosis.
Fractalkine/CX3CL1 is a unique chemokine that works as a leukocyte chemoattractant and …

The mechanism of peritoneal fibrosis in patients on continuous ambulatory peritoneal
dialysis (CAPD) is poorly elucidated. We investigated the cellular mechanism of high …

High glucose–induced PKC activation mediates TGF-β1 and fibronectin synthesis by
peritoneal mesothelial cells. Background Progressive peritoneal fibrosis, membrane …

Background. Depending on the cytokine microenvironment, macrophages (Mφ) can adopt a
proinflammatory (M1) or a profibrotic (M2) phenotype characterized by the expression of cell …

Peritoneal fibrosis (PF) is a frequent complication of peritoneal dialysis (PD) accompanied
by the infiltration of inflammatory cells. Recently, the function of macrophages in an …

Background Peritoneal fibrosis is a serious complication of long-term peritoneal dialysis,
and yet the precise pathogenic mechanisms of peritoneal fibrosis remain unknown …