Here, we present a major advance of the OrthoFinder method. This extends OrthoFinder's high accuracy orthogroup inference to provide phylogenetic inference of orthologs, rooted …
Background OMA is a project that aims to identify orthologs within publicly available, complete genomes. With 657 genomes analyzed to date, OMA is one of the largest projects …
Background Orthologs (genes that have diverged after a speciation event) tend to have similar function, and so their prediction has become an important component of comparative …
Ortholog inference has fundamental importance across the biological sciences, underpinning phylogenetics, comparative genomics and prediction of gene function. We …
Annotating coding genes and inferring orthologs are two classical challenges in genomics and evolutionary biology that have traditionally been approached separately, limiting …
Achieving high accuracy in orthology inference is essential for many comparative, evolutionary and functional genomic analyses, yet the true evolutionary history of genes is …
Motivation Accurate orthology inference is a fundamental step in many phylogenetics and comparative analysis. Many methods have been proposed, including OMA (Orthologous …
Motivation: Inference of the evolutionary relation between proteins, in particular the identification of orthologs, is a central problem in comparative genomics. Several large-scale …
Background Accurate identification of orthologs is crucial for evolutionary studies and for functional annotation. Several algorithms have been developed for ortholog delineation, but …