Chronic administration of d-galactose (d-gal) is widely used to mimic the process of brain
aging; however, the neural mechanisms are still poorly understood. In this study, we …

Rodent chronically injected with d-galactose (d-gal) has been used as an animal aging
model for brain aging or anti-aging pharmacology research. However, the dosage of d-gal …

D-galactose has been widely used in aging research because of its efficacy in inducing
senescence and accelerating aging in animal models. The present study investigated the …

Rodent chronically treated with d-galactose (d-gal) is increasingly used in pharmacological
studies on aging; however, its mechanism remains unclear. The present study investigated …

Astrocytes play multiple roles in physiological and pathological conditions in brain.
However, little is known about the alterations of astrocytes in age-related changes, and few …

Abstract d-Galactose (d-gal) is a reducing sugar that can be used to mimic the
characteristics of aging in rodents; however, the effects of d-gal administration by oral route …

Abstract D-galactose (d-gal) is broadly used in animal aging studies as its chronic
administration mimics learning and memory impairments related to aging in humans …

Aims d-Galactose (d-gal) induced accelerated senescence has been used to develop an
aging model for brain. Previously, long term administration of a wide range of doses has …

Largely as a consequence of changes in modern lifestyle, a significant proportion of global
population have become obese. When obese people grow old, pathologies aggravate …

Accumulated evidence indicates chronic systemic injection of D-galactose mimics aging
progress induced by oxidative stress. We addressed whether memory impairment in this …