Stroke is the leading cause of disability and thesecond leading cause of death worldwide.
With the global population aged 65 and over growing faster than all other age groups, the …

Acute ischaemic stroke accounts for 6.5 million deaths per year, and by 2030 will result in
the annual loss of over 200 million disability-adjusted life years globally. There have been …

Background Neuroprotection for ischemic stroke is a growing field, built upon the elucidation
of the biochemical pathways of ischemia first studied in the 1970s. Beginning in the early …

Stroke is a leading cause of disability in the US. Although there has been significant
progress in the area of medical and surgical thrombolytic technologies, neuroprotective …

Stroke is one of the leading causes of death and disability worldwide. Current treatment
strategies for ischemic stroke primarily focus on reducing the size of ischemic damage and …

Stroke is the second most common cause of global death following coronary artery disease.
Time is crucial in managing stroke to reduce the rapidly progressing insult of the ischemic …

We search for ischemic stroke treatment knowing we have failed—intensely and often—to
translate mechanistic knowledge into treatments that alleviate our patients' functional …

Ischemic stroke is the main cause of death and the most common cause of acquired physical
disability worldwide. Recent demographic changes increase the relevance of stroke and its …

Neuroprotection aims to prevent salvageable neurons from dying. Despite showing efficacy
in experimental stroke studies, the concept of neuroprotection has failed in clinical trials …

Abundant preclinical studies have identified multiple mechanisms of ischemic brain injury
and have provided proof of principle that strategies designed to counter these mechanisms …