Kruppel-associated box zinc-finger proteins (KRAB-ZFPs) make up the largest family of transcription factors in humans. These proteins emerged in the last common ancestor of …
PY Helleboid, M Heusel, J Duc, C Piot… - The EMBO …, 2019 - embopress.org
Krüppel‐associated box (KRAB)‐containing zinc finger proteins (KZFP s) are encoded in the hundreds by the genomes of higher vertebrates, and many act with the heterochromatin …
O Rosspopoff, D Trono - Trends in Genetics, 2023 - cell.com
Canonical Krüppel-associated box (KRAB)-containing zinc finger proteins (KZFPs) act as major repressors of transposable elements (TEs) via the KRAB-mediated recruitment of the …
The human genome encodes some 350 Krüppel-associated box (KRAB) domain-containing zinc-finger proteins (KZFPs), the products of a rapidly evolving gene family that has been …
G Ecco, M Cassano, A Kauzlaric, J Duc, A Coluccio… - Developmental cell, 2016 - cell.com
KRAB-containing zinc finger proteins (KRAB-ZFPs) are early embryonic controllers of transposable elements (TEs), which they repress with their cofactor KAP1 through histone …
A Lupo, E Cesaro, G Montano, D Zurlo, P Izzo… - Current …, 2013 - ingentaconnect.com
Zinc finger proteins containing the Kruppel associated box (KRAB-ZFPs) constitute the largest individual family of transcriptional repressors encoded by the genomes of higher …
M Bruno, M Mahgoub… - Annual Review of …, 2019 - annualreviews.org
Nearly half of the human genome consists of endogenous retroelements (EREs) and their genetic remnants, a small fraction of which carry the potential to propagate in the host …
AC Groner, S Meylan, A Ciuffi, N Zangger… - PLoS …, 2010 - journals.plos.org
Krüppel-associated box domain-zinc finger proteins (KRAB–ZFPs) are tetrapod-specific transcriptional repressors encoded in the hundreds by the human genome. In order to …
J de Tribolet-Hardy, CW Thorball, R Forey… - Genome …, 2023 - genome.cshlp.org
Krüppel-associated box (KRAB) domain-containing zinc finger proteins (KZFPs) are one of the largest groups of transcription factors encoded by tetrapods, with 378 members in …