In clinical genomics, the continuous evolution of bioinformatic algorithms and sequencing
platforms makes it beneficial to store patients' complete aligned genomic data in addition to …

Geneticists prefer to store patients' aligned, raw genomic data, in addition to their variant
calls (compact and summarized form of the raw data), mainly because of the immaturity of …

The ever-increasing growth of high-throughput sequencing technologies has led to a great
acceleration of medical and biological research and discovery. As these platforms advance …

Genomic data alignment, a fundamental operation in sequencing, can be utilized to map
reads into a reference sequence, query on a genomic database and perform genetic tests …

As the cost of human full genome sequencing continues to fall, we will soon witness a
prodigious amount of human genomic data in the public cloud. To protect the confidentiality …

Background Cloud computing is becoming the preferred solution for efficiently dealing with
the increasing amount of genomic data. Yet, outsourcing storage and processing sensitive …

Genomic data is being produced rapidly by both individuals and enterprises and needs to
be outsourced from local machines to a cloud for better flexibility. Outsourcing also …

Sequencing thousands of human genomes has enabled breakthroughs in many areas,
among them precision medicine, the study of rare diseases, and forensics. However, mass …

Background The revolution in DNA sequencing technologies over the past decade has
made it feasible to sequence an individual's whole genome at a relatively low cost. The …

Substring searching on gene sequence data is widely used for analyzing the association
between a list of gene mutations and a specific disease. As substring search usually has a …