Schizophrenia is a complex disease related to combination and interactions between
genetic and environmental factors, with an epigenetic influence. After the development of the …

Whether the etiology of schizophrenia remains unknown, its multifactorial aspect is
conversely now well admitted. However, most preclinical models of the disease still rely on a …

Cross-validated animal models for schizophrenia are crucial to comprehend the cause,
pathophysiology, and behavioral and biological features of the disease, to advance …

Schizophrenia is a chronic, severe and disabling brain disorder that affects more than 21
million people around the world. Despite a tremendous amount of research effort, the …

Schizophrenia is a heterogeneous psychiatric disorder that is poorly treated with current
therapies. In this brief review, we provide an update regarding the use of animal models to …

Animal models of schizophrenia and major psychiatric disorders have been sought for
decades. As it is clear that schizophrenia is a uniquely human disease, animal models are …

Schizophrenia is a severe psychiatric disorder that is characterized by positive and negative
symptoms and cognitive impairments. The etiology of the disorder is complex, and it is …

Schizophrenia is a chronic debilitating brain disorder characterized by a complex set of
perceptual and behavioural symptoms that severely disrupt and undermine the patient's …

Current research into schizophrenia has remained highly fragmented, much like the clinical
presentation of the disease itself. Differing theories as to the cause and progression of …

Schizophrenia is a relatively common but serious mental illness that results in a heavy
burden to patients, their families, and society. The disease can be triggered by multiple …