Background Polygenic scores—which quantify inherited risk by integrating information from
many common sites of DNA variation—may enable a tailored approach to clinical medicine …

Background Polygenic risk scores (PRS), which offer information about genomic risk for
common diseases, have been proposed for clinical implementation. The ways in which PRS …

Polygenic scores (PGS) are primed for use in personalized risk assessments for common,
complex conditions and population health screening. Although there is growing evidence …

We sought to explore individuals' motivations for using their direct-to-consumer genetic
testing data to generate polygenic risk scores (PRSs) using a not-for-profit third-party tool …

Purpose As polygenic risk scores (PRS) emerge as promising tools to inform clinical care,
there is a pressing need for patient-centered evidence to guide their implementation …

With the emergence of electronic medical records and patient portals, patients are
increasingly able to access their health records, including laboratory reports. However …

Polygenic risk scores (PRS) have potential to improve health care by identifying individuals
that have elevated risk for common complex conditions. Use of PRS in clinical practice …

Despite early predictions and rapid progress in research, the introduction of personal
genomics into clinical practice has been slow. Several factors contribute to this translational …

Purpose Examination of patients' responses to direct-to-consumer genetic susceptibility tests
is needed to inform clinical practice. This study examined patients' recall and interpretation …

Has the Genome Granted Our Wish Yet? Interpretation of polygenic risk scores will someday
become an accepted part of clinical practice—but not just yet. It is, however, time to evaluate …