hSK4, a member of a novel subfamily of calcium-activated potassium channels

WJ Joiner, LY Wang, MD Tang… - Proceedings of the …, 1997 - National Acad Sciences
The gene for hSK4, a novel human small conductance calcium-activated potassium
channel, or SK channel, has been identified and expressed in Chinese hamster ovary cells …

Small Conductance Ca2+‐Activated K+ Channels Formed by the Expression of Rat SK1 and SK2 Genes in HEK 293 Cells

DCH Benton, AS Monaghan, R Hosseini… - The Journal of …, 2003 - Wiley Online Library
The rat SK1 gene (rSK1) does not form functional Ca2+‐activated potassium channels when
expressed alone in mammalian cell lines. Using a selective antibody to the rSK1 subunit …

[HTML][HTML] The SK3 subunit of small conductance Ca2+-activated K+ channels interacts with both SK1 and SK2 subunits in a heterologous expression system

AS Monaghan, DCH Benton, PK Bahia… - Journal of Biological …, 2004 - ASBMB
The aim of this study was to determine whether functional heteromeric channels can be
formed by co-assembly of rat SK3 (rSK3) potassium channel subunits with either SK1 or SK2 …

[HTML][HTML] A novel isoform of SK2 assembles with other SK subunits in mouse brain

T Strassmaier, CT Bond, CA Sailer, HG Knaus… - Journal of Biological …, 2005 - ASBMB
The SK2 subtype of small conductance Ca 2+-activated K+ channels is widely distributed
throughout the central nervous system and modulates neuronal excitability by contributing to …

Cloning and tissue-specific expression of five voltage-gated potassium channel cDNAs expressed in rat heart.

SL Roberds, MM Tamkun - Proceedings of the National …, 1991 - National Acad Sciences
Five distinct K+ channel cDNA molecules (RK1 to RK5) were cloned from either rat heart or
rat aorta cDNA libraries. Four of the channels, RK1 to RK4, are similar or identical to Shaker …

[HTML][HTML] Differential expression of small-conductance Ca2+-activated K+ channels SK1, SK2, and SK3 in mouse atrial and ventricular myocytes

D Tuteja, D Xu, V Timofeyev, L Lu… - American Journal …, 2005 - journals.physiology.org
Abstract Small-conductance Ca 2+-activated K+ channels (SK channels, K Ca channels)
have been reported in excitable cells, where they aid in integrating changes in intracellular …

Comparative immunohistochemical distribution of three small-conductance Ca2+-activated potassium channel subunits, SK1, SK2, and SK3 in mouse brain

CA Sailer, WA Kaufmann, J Marksteiner… - Molecular and Cellular …, 2004 - Elsevier
To investigate the distribution of all three SK channel subunits in the mouse central nervous
system, we performed immunohistochemistry using sequence-specific antibodies directed …

Pharmacological characterization of small‐conductance Ca2+‐activated K+ channels stably expressed in HEK 293 cells

D Strøbæk, TD Jørgensen… - British journal of …, 2000 - Wiley Online Library
Three genes encode the small‐conductance Ca2+‐activated K+ channels (SK channels).
We have stably expressed hSK1 and rSK2 in HEK 293 cells and addressed the …

Organization and regulation of small conductance Ca2+-activated K+ channel multiprotein complexes

D Allen, B Fakler, J Maylie… - Journal of Neuroscience, 2007 - Soc Neuroscience
Small conductance Ca2+-activated K+ channels (SK channels) are complexes of four α pore-
forming subunits each bound by calmodulin (CaM) that mediate Ca2+ gating. Proteomic …

The pharmacology of hSK1 Ca2+‐activated K+ channels expressed in mammalian cell lines

M Shah, DG Haylett - British journal of pharmacology, 2000 - Wiley Online Library
The pharmacology of hSK1, a small conductance calcium‐activated potassium channel, was
studied in mammalian cell lines (HEK293 and COS‐7). In these cell types, hSK1 forms an …