[HTML][HTML] Gut microbiota: critical controller and intervention target in brain aging and cognitive impairment

H Li, J Ni, H Qing - Frontiers in aging neuroscience, 2021 - frontiersin.org
The current trend for the rapid growth of the global aging population poses substantial
challenges for society. The human aging process has been demonstrated to be closely …

The gut microbiota is an emerging target for improving brain health during ageing

M Boehme, KE Guzzetta, C Wasén, LM Cox - Gut microbiome, 2023 - cambridge.org
The gut microbiota plays crucial roles in maintaining the health and homeostasis of its host
throughout lifespan, including through its ability to impact brain function and regulate …

[HTML][HTML] A review of the preclinical and clinical studies on the role of the gut microbiome in aging and neurodegenerative diseases and its modulation

HM Hashim, S Makpol - Frontiers in cellular neuroscience, 2022 - frontiersin.org
As the world population ages, the burden of age-related health problems grows, creating a
greater demand for new novel interventions for healthy aging. Advancing aging is related to …

[HTML][HTML] The influence of gut microbiota alteration on age-related neuroinflammation and cognitive decline

AS Alsegiani, ZA Shah - Neural Regeneration Research, 2022 - journals.lww.com
Recent emerging research on intestinal microbiota and its contribution to the central nervous
system during health and disease has attracted significant attention. Age-related intestinal …

[HTML][HTML] Of microbes and minds: a narrative review on the second brain aging

R Calvani, A Picca, MR Lo Monaco, F Landi… - Frontiers in …, 2018 - frontiersin.org
In recent years, an extensive body of literature focused on the gut–brain axis and the
possible role played by the gut microbiota in modulating brain morphology and function from …

Gut dysbiosis and age-related neurological diseases; an innovative approach for therapeutic interventions

A Holmes, C Finger, D Morales-Scheihing, J Lee… - Translational …, 2020 - Elsevier
The gut microbiota is a complex ecosystem of bacteria, fungi, and viruses that acts as a
critical regulator in microbial, metabolic, and immune responses in the host organism …

The gut microbiome as a therapeutic target for cognitive impairment

Y Sun, LC Baptista, LM Roberts… - The Journals of …, 2020 - academic.oup.com
Declining cognitive functions in older individuals have enormous emotional, clinical, and
public health consequences. Thus, therapeutics for preserving function and keeping older …

The contribution of age-related changes in the gut-brain axis to neurological disorders

R Khan, CM Di Gesù, J Lee, LD McCullough - Gut microbes, 2024 - Taylor & Francis
Trillions of microbes live symbiotically in the host, specifically in mucosal tissues such as the
gut. Recent advances in metagenomics and metabolomics have revealed that the gut …

The gut microbiota and nervous system: Age-defined and age-defying

AA Madison, JK Kiecolt-Glaser - Seminars in cell & developmental biology, 2021 - Elsevier
Even healthy older adults experience gastrointestinal (GI) and neurological changes. In fact,
the aging process of these two systems are interrelated due the extensive, multifaceted …

Role of gut-brain axis, gut microbial composition, and probiotic intervention in Alzheimer's disease

P Kesika, N Suganthy, BS Sivamaruthi, C Chaiyasut - Life sciences, 2021 - Elsevier
Gut microbiota represents a diverse and dynamic population of microorganisms harboring
the gastrointestinal tract, which influences the host health and disease. Gut microbiota …