Causal relationship between immune cells and prostate cancer: a Mendelian randomization study

Z Ye, X Deng, J Zhang, R Shao, C Song… - Frontiers in Cell and …, 2024 - frontiersin.org
Introduction: Despite the abundance of research indicating the participation of immune cells
in prostate cancer development, establishing a definitive cause-and-effect relationship has …

Association between circulating immune cells and the risk of prostate cancer: a Mendelian randomization study

X Hao, C Ren, H Zhou, M Li, H Zhang… - Frontiers in …, 2024 - frontiersin.org
Background There is still limited research on the association between immune cells and the
risk of prostate cancer. Further investigations are warranted to comprehend the intricate …

Causal associations of immune cells with benign prostatic hyperplasia: insights from a Mendelian randomization study

T Li, Y Zhang, Z Zhou, Y Zhang, X Song, X Zhou… - World Journal of …, 2024 - Springer
Background Previous research has focused on the association between immune cells and
the development of benign prostatic hyperplasia (BPH). Nevertheless, the causal …

Differences of the immune cell landscape between normal and tumor tissue in human prostate

E Zhang, F Dai, Y Mao, W He, F Liu, W Ma… - Clinical and Translational …, 2020 - Springer
Background Over the past few decades, immunological checkpoint therapy has been an
increasingly prominent strategy in the treatment of tumors, including prostate cancer (PC) …

Immune-related genes are prognostic markers for prostate cancer recurrence

M Fu, Q Wang, H Wang, Y Dai, J Wang, W Kang… - Frontiers in …, 2021 - frontiersin.org
Background Prostate cancer (PCa) is an immune-responsive disease. The current study
sought to explore a robust immune-related prognostic gene signature for PCa. Methods …

The landscape of immune cells infiltrating in prostate cancer

Z Wu, H Chen, W Luo, H Zhang, G Li, F Zeng… - Frontiers in …, 2020 - frontiersin.org
Background This study was to explore the infiltration pattern of immune cells in the prostate
cancer (PCa) microenvironment and evaluate the possibility of specific infiltrating immune …

The immune landscape of prostate cancer and nomination of PD-L2 as a potential therapeutic target

SG Zhao, J Lehrer, SL Chang, R Das… - JNCI: Journal of the …, 2019 - academic.oup.com
Background Immunotherapy has been less successful in treating prostate cancer than other
solid tumors. We sought to better understand the immune landscape in prostate cancer and …

Role of tumor-associated immune cells in prostate cancer: angel or devil?

SQ Wu, H Su, YH Wang, XK Zhao - Asian journal of andrology, 2019 - journals.lww.com
Prostate cancer is the most common malignancy in the reproductive system of older males.
Androgen deprivation therapy (ADT) is an important treatment for prostate cancer patients …

Comparative genomics reveals distinct immune-oncologic pathways in African American men with prostate cancer

S Awasthi, A Berglund, J Abraham-Miranda… - Clinical Cancer …, 2021 - AACR
Purpose: The role of immune-oncologic mechanisms of racial disparities in prostate cancer
remains understudied. Limited research exists to evaluate the molecular underpinnings of …

Causal relationship between immune cell phenotypes and risk of biliary tract cancer: evidence from Mendelian randomization analysis

YL Hu, K Wang, Y Chen, Y Jin, Q Guo… - Frontiers in …, 2024 - frontiersin.org
Background Biliary tract cancer stands as a prevalent illness, posing significant risks to
human health, where immune cells are pivotal in both its development and recovery …