Chest computed tomography characteristics of critically Ill COVID-19 patients with auto-antibodies against type I interferons
B Lafont Rapnouil, Y Zaarour, R Arrestier… - Journal of Clinical …, 2024 - Springer
Purpose Patients with auto-antibodies neutralizing type I interferons (anti-IFN auto-Abs) are
at risk of severe forms of coronavirus disease 19 (COVID-19). The chest computed …
at risk of severe forms of coronavirus disease 19 (COVID-19). The chest computed …
Auto-antibodies against type I IFNs in> 10% of critically ill COVID-19 patients: a prospective multicentre study
R Arrestier, P Bastard, T Belmondo, G Voiriot… - Annals of Intensive …, 2022 - Springer
Abstract Background Auto-antibodies (auto-Abs) neutralizing type I interferons (IFN) have
been found in about 15% of critical cases COVID-19 pneumonia and less than 1% of mild or …
been found in about 15% of critical cases COVID-19 pneumonia and less than 1% of mild or …
Early and rapid identification of COVID-19 patients with neutralizing type I interferon auto-antibodies
B Akbil, T Meyer, P Stubbemann, C Thibeault… - Journal of clinical …, 2022 - Springer
Purpose Six to 19% of critically ill COVID-19 patients display circulating auto-antibodies
against type I interferons (IFN-AABs). Here, we establish a clinically applicable strategy for …
against type I interferons (IFN-AABs). Here, we establish a clinically applicable strategy for …
Pre-existing autoantibodies neutralizing high concentrations of type I interferons in almost 10% of COVID-19 patients admitted to intensive care in Barcelona
X Solanich, R Rigo-Bonnin, VD Gumucio… - Journal of clinical …, 2021 - Springer
Background It is important to predict which patients infected by SARS-CoV-2 are at higher
risk of life-threatening COVID-19. Several studies suggest that neutralizing auto-antibodies …
risk of life-threatening COVID-19. Several studies suggest that neutralizing auto-antibodies …
Antibodies against type I interferon: detection and association with severe clinical outcome in COVID‐19 patients
D Goncalves, M Mezidi, P Bastard… - Clinical & …, 2021 - Wiley Online Library
Objectives Impairment of type I interferon (IFN‐I) immunity has been reported in critically ill
COVID‐19 patients. This defect can be explained in a subset of patients by the presence of …
COVID‐19 patients. This defect can be explained in a subset of patients by the presence of …
Autoantibodies neutralizing type I interferons in 20% of COVID-19 deaths in a French hospital
A Chauvineau-Grenier, P Bastard, A Servajean… - Journal of Clinical …, 2022 - Springer
Recent studies reported the presence of pre-existing autoantibodies (auto-Abs) neutralizing
type I interferons (IFNs) in at least 15% of patients with critical COVID-19 pneumonia. In one …
type I interferons (IFNs) in at least 15% of patients with critical COVID-19 pneumonia. In one …
Prevalence of type-1 interferon autoantibodies in adults with non-COVID-19 acute respiratory failure
R Ghale, N Spottiswoode, MS Anderson, A Mitchell… - Respiratory …, 2022 - Springer
Auto-antibodies (Abs) to type I interferons (IFNs) are found in up to 25% of patients with
severe COVID-19, and are implicated in disease pathogenesis. It has remained unknown …
severe COVID-19, and are implicated in disease pathogenesis. It has remained unknown …
Early and rapid identification of COVID-19 patients with neutralizing type I-interferon auto-antibodies by an easily implementable algorithm
B Akbil, T Meyer, P Stubbemann, C Thibeault… - Medrxiv, 2021 - medrxiv.org
Purpose Six-19% of critically ill COVID-19 patients display circulating auto-antibodies
against type I interferons (IFN-AABs). Here, we establish a clinically applicable strategy for …
against type I interferons (IFN-AABs). Here, we establish a clinically applicable strategy for …
Neutralizing autoantibodies to type I IFNs in> 10% of patients with severe COVID-19 pneumonia hospitalized in Madrid, Spain
J Troya, P Bastard, L Planas-Serra, P Ryan… - Journal of clinical …, 2021 - Springer
Background In a recent study, autoantibodies neutralizing type I interferons (IFNs) were
present in at least 10% of cases of critical COVID-19 pneumonia. These autoantibodies …
present in at least 10% of cases of critical COVID-19 pneumonia. These autoantibodies …
Neutralizing type I interferon autoantibodies in Japanese patients with severe COVID-19
S Eto, Y Nukui, M Tsumura, Y Nakagama… - Journal of Clinical …, 2022 - Springer
Purpose Autoantibodies (aAbs) to type I interferons (IFNs) have been found in less than 1%
of individuals under the age of 60 in the general population, with the prevalence increasing …
of individuals under the age of 60 in the general population, with the prevalence increasing …