Reduction–oxidation reactions are essential to cellular homeostasis. Oxidative stress
transcends physiological antioxidative system damage to biomolecules, including nucleic …

Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease (MND) and Lou
Gehrig's disease, is characterized by a loss of the lower motor neurons in the spinal cord …

The cellular redox state, or balance between cellular oxidation and reduction reactions,
serves as a vital antioxidant defence system that is linked to all important cellular activities …

A mutant form of the ubiquitous copper/zinc superoxide dismutase (SOD1) protein has been
found in some patients with amyotrophic lateral sclerosis (ALS). We monitored oxidative …

The mechanisms underlying motoneuron degeneration in amyotrophic lateral sclerosis
(ALS), a neurodegenerative disorder that affects the motor system with progressive …

Oxidative stress has been reported to be involved in the onset and development of
amyotrophic lateral sclerosis (ALS). Data from clinical studies have highlighted increased …

Oxidative stress, induced by an imbalance of free radicals, incites neurodegeneration in
Amyotrophic Lateral Sclerosis (ALS). In fact, a mutation in antioxidant enzyme superoxide …

Amyotrophic lateral sclerosis (ALS) affects motor neurons in the cerebral cortex, brainstem
and spinal cord and leads to death due to respiratory failure within three to five years …

Significance: Amyotrophic lateral sclerosis (ALS) is due to degeneration of upper and lower
motor neurons in the anterior horn of the spinal cord and in the motor cortex. Mechanisms …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with the progressive
loss of motor neurons, leading to a fatal paralysis. According to whether there is a family …