Bioprinted osteogenic and vasculogenic patterns for engineering 3D bone tissue

B Byambaa, N Annabi, K Yue… - Advanced …, 2017 - Wiley Online Library
Fabricating 3D large‐scale bone tissue constructs with functional vasculature has been a
particular challenge in engineering tissues suitable for repairing large bone defects. To …

3D bioprinting for vascularized tissue-engineered bone fabrication

F Xing, Z Xiang, PM Rommens, U Ritz - Materials, 2020 - mdpi.com
Vascularization in bone tissues is essential for the distribution of nutrients and oxygen, as
well as the removal of waste products. Fabrication of tissue-engineered bone constructs with …

Prevascularization of 3D printed bone scaffolds by bioactive hydrogels and cell co‐culture

MA Kuss, S Wu, Y Wang, JB Untrauer… - … Research Part B …, 2018 - Wiley Online Library
Vascularization is a fundamental prerequisite for large bone construct development and
remains one of the main challenges of bone tissue engineering. Our current study presents …

[HTML][HTML] 3D bioprinting of prevascularised implants for the repair of critically-sized bone defects

J Nulty, FE Freeman, DC Browe, R Burdis, DP Ahern… - Acta biomaterialia, 2021 - Elsevier
For 3D bioprinted tissues to be scaled-up to clinically relevant sizes, effective
prevascularisation strategies are required to provide the necessary nutrients for normal …

Vascularized bone-mimetic hydrogel constructs by 3D bioprinting to promote osteogenesis and angiogenesis

T Anada, CC Pan, AM Stahl, S Mori, J Fukuda… - International journal of …, 2019 - mdpi.com
Bone is a highly vascularized tissue with a unique and complex structure. Long bone
consists of a peripheral cortical shell containing a network of channels for vascular …

Dual 3D printing for vascularized bone tissue regeneration

SY Hann, H Cui, T Esworthy, X Zhou, S Lee… - Acta Biomaterialia, 2021 - Elsevier
The development of sufficient vascular networks is crucial for the successful fabrication of
tissue constructs for regenerative medicine, as vascularization is essential to perform the …

Bioprinted osteon-like scaffolds enhance in vivo neovascularization

C Piard, H Baker, T Kamalitdinov, J Fisher - Biofabrication, 2019 - iopscience.iop.org
Bone tissue engineers are facing a daunting challenge when attempting to fabricate bigger
constructs intended for use in the treatment of large bone defects, which is the …

Key components of engineering vascularized 3-dimensional bioprinted bone constructs

F Shahabipour, N Ashammakhi, RK Oskuee… - Translational …, 2020 - Elsevier
Vascularization has a pivotal role in engineering successful tissue constructs. However, it
remains a major hurdle of bone tissue engineering, especially in clinical applications for the …

A synergistic approach to the design, fabrication and evaluation of 3D printed micro and nano featured scaffolds for vascularized bone tissue repair

B Holmes, K Bulusu, M Plesniak, LG Zhang - Nanotechnology, 2016 - iopscience.iop.org
Abstract 3D bioprinting has begun to show great promise in advancing the development of
functional tissue/organ replacements. However, to realize the true potential of 3D bioprinted …

[HTML][HTML] 3D bioprinting of in situ vascularized tissue engineered bone for repairing large segmental bone defects

M Shen, L Wang, Y Gao, L Feng, C Xu, S Li, X Wang… - Materials Today Bio, 2022 - Elsevier
Large bone defects remain an unsolved clinical challenge because of the lack of effective
vascularization in newly formed bone tissue. 3D bioprinting is a fabrication technology with …