The continued evolution of SARS-CoV-2 underscores the need to understand qualitative
aspects of the humoral immune response elicited by spike immunization. Here, we …

Vaccination of SARS-CoV-2 convalescent individuals generates broad and potent antibody
responses. Here, we isolate 459 spike-specific monoclonal antibodies (mAbs) from two …

Dissecting the evolution of memory B cells (MBCs) against SARS-CoV-2 is critical for
understanding antibody recall upon secondary exposure. Here, we used single-cell …

Despite the success of COVID-19 vaccines in preventing infection and/or severe disease,
there has been an increase in SARS-CoV-2 infections in vaccinated individuals owing to the …

Delineating the origins and properties of antibodies elicited by SARS-CoV-2 infection and
vaccination is critical for understanding their benefits and potential shortcomings. Therefore …

Neutralizing antibodies are a key component in protective humoral immunity against SARS-
CoV-2. Currently, available technologies cannot track epitope-specific antibodies in global …

Understanding the quality of immune repertoire triggered during natural infection can
provide vital clues that form the basis for development of a humoral immune response in …

Despite the success of COVID-19 vaccines in preventing infection and/or severe disease,
with the emergence of SARS-CoV-2 variants of concern (VOC) which encode mutations in …

SARS-CoV-2 infection or vaccination produces neutralizing antibody responses that
contribute to better clinical outcomes. The receptor-binding domain (RBD) and the N …

The reduced effectiveness of COVID-19 vaccines due to the emergence of variants of
concern (VOCs) necessitated the use of vaccine boosters to bolster protection against …