[HTML][HTML] Efficacy and safety of tocilizumab in COVID-19 patients: a living systematic review and meta-analysis

IM Tleyjeh, Z Kashour, M Damlaj, M Riaz… - Clinical Microbiology …, 2021 - Elsevier
Objectives Cytokine release syndrome with elevated interleukin-6 (IL-6) levels is associated
with multiorgan damage and death in severe coronavirus disease 2019 (COVID-19). Our …

[HTML][HTML] Efficacy and safety of tocilizumab in COVID-19 patients: a living systematic review and meta-analysis, first update

IM Tleyjeh, Z Kashour, M Riaz, L Hassett… - Clinical Microbiology …, 2021 - Elsevier
Objectives Cytokine release syndrome with elevated interleukin-6 (IL-6) levels is associated
with multiorgan damage and death in severe coronavirus disease 2019 (COVID-19). Our …

Tocilizumab in COVID-19: a meta-analysis, trial sequential analysis, and meta-regression of randomized-controlled trials

TAC Snow, N Saleem, G Ambler, E Nastouli… - Intensive Care …, 2021 - Springer
Abstract Purpose Interleukin-6 (IL-6) levels discriminate between patients with mild and
severe COVID-19, making IL-6 inhibition an attractive therapeutic strategy. We conducted a …

Efficacy and safety of Tocilizumab in severe and critical COVID-19: A Systematic Review and Meta-Analysis

S Rezaei, B Fatemi, Z Karimi Majd… - Expert review of …, 2021 - Taylor & Francis
Objectives Currently published papers and clinical guidelines regarding the effects of
tocilizumab in severe and critical COVID-19 are contradictory. The aim of this meta-analysis …

Tocilizumab in hospitalized patients with COVID-19: a meta analysis of randomized controlled trials

V Selvaraj, MS Khan, C Bavishi, K Dapaah-Afriyie… - Lung, 2021 - Springer
Background To date, only dexamethasone has been shown to reduce mortality in
coronavirus disease-19 (COVID-19) patients. Tocilizumab has been recently added to the …

Tocilizumab administration for the treatment of hospitalized patients with COVID‐19: a systematic review and meta‐analysis

C Kyriakopoulos, G Ntritsos, A Gogali, H Milionis… - …, 2021 - Wiley Online Library
Tocilizumab has been repurposed against the 'cytokine storm'in the setting of coronavirus
disease 2019 (COVID‐19). Our aim was to evaluate the efficacy of tocilizumab in the …

Tocilizumab for severe COVID-19: a systematic review and meta-analysis

SH Lan, CC Lai, HT Huang, SP Chang, LC Lu… - International journal of …, 2020 - Elsevier
This systemic review and meta-analysis aimed to assess the efficacy of tocilizumab for the
treatment of severe coronavirus disease 2019 (COVID-19). Candidate studies up to 24 May …

Tocilizumab treatment for COVID-19 patients: a systematic review and meta-analysis

Q Wei, H Lin, RG Wei, N Chen, F He, DH Zou… - Infectious diseases of …, 2021 - Springer
Abstract Background Coronavirus disease 2019 (COVID-19) has killed over 2.5 million
people worldwide, but effective care and therapy have yet to be discovered. We conducted …

[HTML][HTML] Effects of tocilizumab on mortality in hospitalized patients with COVID-19: a multicentre cohort study

J Martínez-Sanz, A Muriel, R Ron, S Herrera… - Clinical Microbiology …, 2021 - Elsevier
Objectives Tocilizumab has been proposed as a candidate therapy for patients with severe
coronavirus disease 2019 (COVID-19), especially among those with higher systemic …

Beneficial and harmful outcomes of tocilizumab in severe COVID‐19: a systematic review and meta‐analysis

M Rubio‐Rivas, CG Forero… - … : The Journal of …, 2021 - Wiley Online Library
Introduction The results of studies of tocilizumab (TCZ) in COVID‐19 are contradictory. Our
study aims to update medical evidence from controlled observational studies and …