Th17 cells play vital role during pathogenesis of leprosy reactions. Previously, we have
reported that IL-23 is involved in Th17 cells differentiation. Subsequently, our group also …

Leprosy type 1 reaction (T1R) is a cell-mediated inflammatory reaction which involves skin
and peripheral nerves in leprosy. Lesions with T1R have higher production of IL-17 cytokine …

Leprosy is an infectious disease caused by non‐cultivable bacteria Mycobacterium leprae.
Th17 cells play vital roles during pathogenesis of leprosy reactions and IL‐23 is involved in …

Background Leprosy reactions appear episodically in leprosy patients, which lead to high
inflammation, morbidity and peripheral nerve damage. The role of Th17 cell has been well …

Abstract Type 1 reactions (T1R) an inflammatory condition, of local skin patches in 30–40%
leprosy patients during the course of MDT. IL-17A and IL-17F play an important role in …

Mycobacterium leprae is a kind of disease-causing bacteria and results in leprosy in human.
Gamma delta (γδ) T cell is a T-cell subset that is presented in both human dermis and …

Background Patients with localized tuberculoid and generalized lepromatous leprosy show
respectively Th1 and Th2 cytokine profile. Additionally, other patients in both types of leprosy …

Leprosy is a complex chronic, infectious dermato-neurological disease that affects the skin
and peripheral nerves especially during immuno-inflammatory episodes known as type …

While there are conflicting data concerning interleukin (IL)-17 levels in the serum of patients
with leprosy compared with those in healthy controls, higher levels have been more evident …

Background 50% of leprosy patients suffer from episodes of Type 1/reversal reactions (RR)
and Type 2/Erythema Nodosum Leprosum (ENL) reactions which lead to morbidity and …