Abstract SARS-CoV2 mutants B. 1.1. 7, B. 1.351, and P. 1 contain a key mutation N501Y. B.
1.135 and P. 1 lineages have another mutation, E484K. Here, we decode the effect of these …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants continue to
emerge during the global pandemic and may facilitate escape from current antibody …

SARS-CoV-2 is a betacoronavirus virus responsible for the COVID-19 pandemic. Here, we
determine the X-ray crystal structure of a potent neutralizing monoclonal antibody, CV30 …

Understanding the mechanism for antibody neutralization of SARS-CoV-2 is critical for the
development of effective therapeutics and vaccines. We recently isolated a large number of …

The recently emerged severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) Beta
(B. 1.351) and Gamma (P. 1) variants of concern (VoCs) include a key mutation (N501Y) …

Terminating the SARS-CoV-2 pandemic relies upon pan-global vaccination. Current
vaccines elicit neutralizing antibody responses to the virus spike derived from early isolates …

Abstract SARS-CoV-2 recognizes, via its spike receptor-binding domain (S-RBD), human
angiotensin-converting enzyme 2 (ACE2) to initiate infection. Ecto-domain protein of ACE2 …

Dear Editor, The spread of the SARS-CoV-2 variants, especially the global variants of
concern (VOCs), could seriously dampen our efforts to tackle the COVID-19 pandemic. The …

The highly infectious SARS-CoV-2 variant B. 1.351 that first emerged in South Africa with
triple mutations (N501Y, K417N, and E484K) is globally worrisome. It is known that N501Y …

The recent identification and rise to dominance of the P. 1 and B. 1.351 SARS-CoV-2
variants have brought international concern because they may confer fitness advantages …