Thymic Epithelial Tumor and Immune System: The Role of Immunotherapy

M Perrino, N Cordua, F De Vincenzo, F Borea… - Cancers, 2023 - mdpi.com
Simple Summary Similarly to other solid malignancies, there is a growing interest in testing
immune checkpoint inhibitors (ICIs) for thymic epithelial tumors (TETs). However, the thymus …

Immunotherapy for management of thymic epithelial tumors: a double-edged sword

M Ballman, C Zhao, MJ McAdams, A Rajan - Cancers, 2022 - mdpi.com
Simple Summary Immunotherapy has a rapidly expanding role for the treatment of several
cancers due to durable clinical activity and favorable tolerability. However, the unique …

Understanding the landscape of immunotherapy in thymic epithelial tumors

R Maniar, PJ Loehrer Sr - Cancer, 2023 - Wiley Online Library
Thymic epithelial tumors (TETs) are a rare group of malignancies arising from the thymus.
Surgery remains the foundation of treatment for patients with early‐stage disease. Limited …

[HTML][HTML] Narrative review of immunotherapy in thymic malignancies

JC Benitez, B Besse - Translational Lung Cancer Research, 2021 - ncbi.nlm.nih.gov
Thymomas and thymic carcinomas (TCs)(also known as Thymic Epithelial Tumors or TETs)
are rare cancers and the most frequent masses of the anterior mediastinum. These tumors …

Immunobiology of thymic epithelial tumors: implications for immunotherapy with immune checkpoint inhibitors

V Tateo, L Manuzzi, A De Giglio, C Parisi… - International Journal of …, 2020 - mdpi.com
Thymic epithelial tumors (TETs) are a group of rare thoracic malignancies, including thymic
carcinomas (TC) and thymomas (Tm). Autoimmune paraneoplastic diseases are often …

[HTML][HTML] The efficacy and safety of immunotherapy in thymic epithelial tumors: more effective, more risky: a systematic review

X Song, J Fan, L Zhu, Z Wang, Y He… - Journal of Thoracic …, 2021 - ncbi.nlm.nih.gov
Background Thymic epithelial tumors (TETs) are rare malignant neoplasms originating from
thymic epithelial cells. The current treatment for localized TETs is surgical removal …

Immunotherapy for Thymomas and Thymic Carcinomas: Current Status and Future Directions

A Rajan, AK Sivapiromrat, MJ McAdams - Cancers, 2024 - mdpi.com
Simple Summary Immune checkpoint inhibitors have revolutionized cancer therapy and
improved clinical outcomes. Immunotherapy is now increasingly combined with …

Emerging therapies in thymic epithelial tumors

A Dapergola, G Gomatou, I Trontzas… - Oncology …, 2023 - spandidos-publications.com
Thymic epithelial tumors (TETs), including thymomas and thymic carcinomas, are rare
malignancies arising from the thymus gland. The optimal management requires a …

Balancing the risk of adverse events against the efficacy of immunotherapy in advanced thymic epithelial tumors

B Ohm, W Jungraithmayr - Cancers, 2022 - mdpi.com
Simple Summary Treatment options for advanced thymic malignancies are limited. Immune
checkpoint inhibitors are effective against advanced thymic epithelial tumors, but the …

[HTML][HTML] Immunotherapy in thymic epithelial tumors: tissue predictive biomarkers for immune checkpoint inhibitors

S Lucà, M Accardo, S Campione… - Exploration of Targeted …, 2024 - explorationpub.com
Thymic epithelial tumors (TETs) are rare malignant neoplasms arising in the thymus gland.
Nevertheless, TETs, including thymomas (TMs), thymic carcinomas (TCs), and thymic …