Sacubitril/valsartan: research progress of multi-channel therapy for cardiorenal syndrome

S Wang, Y Wang, Y Deng, J Zhang, X Jiang… - Frontiers in …, 2023 - frontiersin.org
Cardiorenal syndrome (CRS) results from complex interaction between heart and kidneys,
inducing simultaneous acute or chronic dysfunction of these organs. Although its incidence …

[HTML][HTML] Combined levosimendan and sacubitril/valsartan markedly protected the heart and kidney against cardiorenal syndrome in rat

PH Sung, HT Chai, CC Yang, JY Chiang… - Biomedicine & …, 2022 - Elsevier
Background Cardiorenal syndrome (CRS) remains the leading cause of death in
hospitalized patients for all disease entities. Sacubitril/Valsartan (Sac/Val) therapy has been …

[HTML][HTML] Cardiorenal syndrome

P Pai - Hong Kong Journal of Nephrology, 2015 - Elsevier
Patients with cardiorenal syndrome (CRS) suffer from extremely high levels of morbidity and
mortality. The pathophysiology of the CRS involves inter-related hemodynamic and …

The effect of sacubitril/valsartan treatment on cardiac and renal functions of a patient with cardiorenal syndrome type 4 and Stage 5 ckd after more than three years of …

S Cheng, T Zhou, L Yu, Y Chen, Z Zhang… - Frontiers in …, 2022 - frontiersin.org
It is difficult to treat cardiorenal syndrome (CRS) in clinical practice, which is the common
reason for the death of patients. This report aimed to describe the effects of …

Cardiorenal disease: a practical approach

P Caravaca-Pérez, MM Cobo Marcos… - Frontiers in …, 2024 - frontiersin.org
Heart failure and chronic kidney disease are among the most common comorbidities in the
population. Often, both diseases coexist in the same patient, with a deleterious interaction …

Pharmacological approaches to cardio-renal syndrome: a role for the inodilator levosimendan

F Fedele, K Karason… - European Heart Journal …, 2017 - academic.oup.com
Pathological interplay between the heart and kidneys—also known as cardio-renal
syndrome (CRS)—is frequently encountered in heart failure and is linked to worse prognosis …

Cardiorenal syndrome: new developments in the understanding and pharmacologic management

AA House - Clinical Journal of the American Society of …, 2013 - journals.lww.com
Cardiorenal syndromes (CRSs) with bidirectional heart-kidney signaling are increasingly
being recognized for their association with increased morbidity and mortality. In acute CRS …

Kidney and heart interactions during cardiorenal syndrome: a molecular and clinical pathogenic framework

C Napoli, A Casamassimi, V Crudele, T Infante… - Future …, 2011 - Taylor & Francis
The heart and kidney are physiologically interconnected. Cardiorenal syndrome (CRS) is a
pathological disorder where acute or chronic dysfunction in one organ may induce …

Pharmacologic therapies for chronic and acute decompensated heart failure: specific insights on cardiorenal syndromes

F Roubille, M Morena, H Leray-Moragues… - Blood …, 2014 - karger.com
In the setting of cardiorenal syndrome (s)(CRS), the main pathophysiological triggers of
renal disease progression include increases in renal venous pressure, maladaptive …

[HTML][HTML] Emerging treatments of cardiorenal syndrome: an update on pathophysiology and management

D Verma, A Firoz, SKP Garlapati, TSCR Sathi, M Haris… - Cureus, 2021 - ncbi.nlm.nih.gov
Cardiorenal syndrome refers to combined cardiac and renal dysfunction that adversely
impacts both organs and is also associated with severe clinical outcomes. The …