Prostate cancer genomics: recent advances and the prevailing underrepresentation from racial and ethnic minorities

SH Tan, G Petrovics, S Srivastava - International journal of molecular …, 2018 - mdpi.com
Prostate cancer (CaP) is the most commonly diagnosed non-cutaneous cancer and the
second leading cause of male cancer deaths in the United States. Among African American …

Minireview: the molecular and genomic basis for prostate cancer health disparities

IJ Powell, A Bollig-Fischer - Molecular endocrinology, 2013 - academic.oup.com
Despite more aggressive screening across all demographics and gradual declines in
mortality related to prostate cancer (PCa) in the United States, race disparities persist. For …

Genetic and molecular differences in prostate carcinogenesis between African American and Caucasian American men

J Farrell, G Petrovics, DG McLeod… - International journal of …, 2013 - mdpi.com
Prostate cancer is the most common non-skin cancer and the second leading cause of
cancer-related death for men in the United States. Prostate cancer incidence and associated …

Evidence for molecular differences in prostate cancer between African American and Caucasian men

F Khani, JM Mosquera, K Park, M Blattner… - Clinical Cancer …, 2014 - AACR
Purpose: The aim of this study was to compare the frequency of ERG rearrangement, PTEN
deletion, SPINK1 overexpression, and SPOP mutation in prostate cancer in African …

Race and prostate cancer: genomic landscape

C Arenas-Gallo, J Owiredu, I Weinstein… - Nature Reviews …, 2022 - nature.com
In the past 20 years, new insights into the genomic pathogenesis of prostate cancer have
been provided. Large-scale integrative genomics approaches enabled researchers to …

Mutational landscape of aggressive prostate tumors in African American men

KJ Lindquist, PL Paris, TJ Hoffmann, NJ Cardin… - Cancer research, 2016 - AACR
Prostate cancer is the most frequently diagnosed and second most fatal nonskin cancer
among men in the United States. African American men are two times more likely to develop …

[HTML][HTML] Genetic contributions to prostate cancer disparities in men of West African descent

JR Johnson, L Woods-Burnham, SE Hooker Jr… - Frontiers in …, 2021 - frontiersin.org
Prostate cancer (PCa) is the second most frequently diagnosed malignancy and the second
leading cause of death in men worldwide, after adjusting for age. According to the …

[HTML][HTML] Molecular mechanisms involving prostate cancer racial disparity

C Karakas, C Wang, F Deng, H Huang… - American journal of …, 2017 - ncbi.nlm.nih.gov
Prostate cancer (PCa) is the second leading cause of cancer-related deaths in the United
States. The African (AA) descent has greater incidence and mortality rates of PCa as …

Genomic profiling of prostate cancers from men with African and European ancestry

Y Koga, H Song, ZR Chalmers, J Newberg, E Kim… - Clinical Cancer …, 2020 - AACR
Abstract Purpose: African American (AFR) men have the highest mortality rate from prostate
cancer (PCa) compared with men of other racial/ancestral groups. Differences in the …

[HTML][HTML] Genomic, epigenomic, and transcriptomic signatures of prostate cancer between African American and European American patients

C Stevens, A Hightower, SG Buxbaum… - Frontiers in …, 2023 - frontiersin.org
Prostate cancer is the second most common cancer in men in the United States, and racial
disparities are greatly observed in the disease. Specifically, African American (AA) patients …