Deregulation of the polycomb group gene BMI-1 is implicated in the pathogenesis of many
human cancers. In this study, we have investigated if the Ewing sarcoma family of tumors …

The polycomb group protein BMI1 has been shown to support normal stem cell proliferation
via its putative stem cell factor function, but it is not known if BMI1 may also act as a cancer …

Bmi-1 is a member of the Polycomb group family of proteins that function in the epigenetic
silencing of genes governing self-renewal, differentiation, and proliferation. Bmi-1 was first …

BMI‑1 oncogene is a member of the polycomb‑group gene family and a transcriptional
repressor. Overexpression of BMI‑1 has been identified in various human cancer tissues …

Abstract Background The polycomb group (PcG) protein BMI1 is an important regulator of
development. Additionally, aberrant expression of BMI1 has been linked to cancer stem cell …

Background BMI-1 is a member of the polycomb group of genes (PcGs), and it has been
implicated in the development and progression of several malignancies, but its role in …

The polycomb group family protein BMI-1 is overexpressed by and functions as an
oncogene in many different human cancers. We have previously shown that BMI-1 promotes …

The Bmi-1 oncogene is overexpressed in a number of malignancies including breast cancer.
In addition to Bmi-1, mammalian cells also express four other polycomb group (PcG) …

Abstract Bmi-1 and Mel-18 are structural homologues that belong to the Polycomb group of
transcriptional regulators and are believed to stably maintain repression of gene expression …

Bmi-1, a polycomb gene family member, plays an important role in cell cycle regulation, cell
immortalization, and cell senescence. Recently, numerous studies have demonstrated that …