The close association among cardiovascular, metabolic, and kidney diseases suggests a
common pathological basis and significant interaction among these diseases. Metabolic …

Inflammation participates in the pathogenesis of both cancer and cardiovascular disease.
This review examines the mechanistic commonalities between these two scourges of …

Obesity is a major global epidemic that sets the stage for diverse multiple pathologies,
including cardiovascular disease. The obesity-related low grade chronic inflamed milieu is …

Background Organ crosstalk can be defined as the complex and mutual biological
communication between distant organs mediated by signaling factors. Normally, crosstalk …

Aging is associated with immunosenescence and accompanied by a chronic inflammatory
state which contributes to metabolic syndrome, diabetes and their cardiovascular …

Abdominal obesity is a major risk factor for cardiovascular disease, and recent studies
highlight a key role of adipose tissue dysfunction, inflammation, and aberrant adipokine …

The global population above 60 years has been growing exponentially in the last decades,
which is accompanied by an increase in the prevalence of age‐related chronic diseases …

Insights from epidemiological, clinical and basic research are illuminating the interplay
between metabolic disorders, cardiovascular disease (CVD) and kidney dysfunction, termed …

Inter-organ crosstalk plays an essential role in the physiological homeostasis of the heart
and other organs, and requires a complex interaction between a host of cellular, molecular …

Heart failure (HF) patients often suffer from multiple comorbidities, such as diabetes, atrial
fibrillation, depression, chronic obstructive pulmonary disease, and chronic kidney disease …