Extracellular vesicles in malaria: an agglomeration of two decades of research

T Opadokun, P Rohrbach - Malaria Journal, 2021 - Springer
Malaria is a complex parasitic disease, caused by Plasmodium spp. More than a century
after the discovery of malaria parasites, this disease continues to pose a global public health …

The role of extracellular vesicles in malaria biology and pathogenesis

NG Sampaio, L Cheng, EM Eriksson - Malaria Journal, 2017 - Springer
In the past decade, research on the functions of extracellular vesicles in malaria has
expanded dramatically. Investigations into the various vesicle types, from both host and …

Protein profiling of malaria-derived extracellular vesicles reveals distinct subtypes

T Opadokun, J Agyapong, P Rohrbach - Membranes, 2022 - mdpi.com
Malaria is caused by obligate intracellular parasites belonging to the genus Plasmodium.
Red blood cells (RBCs) infected with different stages of Plasmodium spp. release …

Role of extracellular vesicles in cellular cross talk in malaria

KA Babatunde, B Yesodha Subramanian… - Frontiers in …, 2020 - frontiersin.org
Malaria infection caused by the Plasmodium species is a complex disease in which a fine
balance between host and parasite factors determine the disease severity. While in some …

Interplay of extracellular vesicles and other players in cerebral malaria pathogenesis

S Debs, A Cohen, E Hosseini-Beheshti… - … et Biophysica Acta (BBA …, 2019 - Elsevier
Background Malaria is a serious parasitic infection affecting millions of people worldwide
each year. Cerebral malaria is the most severe complication of Plasmodium infections …

Extracellular vesicles could carry an evolutionary footprint in interkingdom communication

R Correa, Z Caballero, LF De León… - Frontiers in Cellular and …, 2020 - frontiersin.org
Extracellular vesicles (EVs) are minute particles secreted by the cells of living organisms.
Although the functional role of EVs is not yet clear, recent work has highlighted their role in …

Extracellular vesicles derived from Plasmodium-infected and non-infected red blood cells as targeted drug delivery vehicles

LN Borgheti-Cardoso, SAA Kooijmans… - International Journal of …, 2020 - Elsevier
Among several factors behind drug resistance evolution in malaria is the challenge of
administering overall doses that are not toxic for the patient but that, locally, are sufficiently …

[HTML][HTML] Proteomic analysis of extracellular vesicles from a Plasmodium falciparum Kenyan clinical isolate defines a core parasite secretome

A Abdi, L Yu, D Goulding, MK Rono, P Bejon… - Wellcome open …, 2017 - ncbi.nlm.nih.gov
Background: Many pathogens secrete effector molecules to subvert host immune responses,
to acquire nutrients, and/or to prepare host cells for invasion. One of the ways that effector …

Extracellular Vesicles Derived from Early and Late Stage Plasmodium falciparum-Infected Red Blood Cells Contain Invasion-Associated Proteins

S Vimonpatranon, S Roytrakul, N Phaonakrop… - Journal of Clinical …, 2022 - mdpi.com
In infectious diseases, extracellular vesicles (EVs) released from a pathogen or pathogen-
infected cells can transfer pathogen-derived biomolecules, especially proteins, to target cells …

Guidelines for the purification and characterization of extracellular vesicles of parasites

C Fernandez‐Becerra, P Xander… - Journal of …, 2023 - Wiley Online Library
Parasites are responsible for the most neglected tropical diseases, affecting over a billion
people worldwide (WHO, 2015) and accounting for billions of cases a year and responsible …