Nitric oxide (NO) is a key signalling molecule in the cardiovascular, immune and central
nervous systems, and crucial steps in the regulation of NO bioavailability in health and …

Nitric oxide (NO) mediates multiple physiological and pathophysiological processes in the
cardiovascular system. Pharmacological compounds that release NO have been useful tools …

Nitric oxide (NO) plays a pivotal role in the maintenance of cardiovascular homeostasis. A
reduction in the bioavailability of endogenous NO, manifest as a decrease in the production …

Nitric oxide (NO) signalling has pleiotropic roles in biology and a crucial function in
cardiovascular homeostasis. Tremendous knowledge has been accumulated on the …

Nitric oxide synthases (NOS) are the enzymes responsible for nitric oxide (NO) generation.
To date, 3 distinct NOS isoforms have been identified: neuronal NOS (NOS1), inducible NOS …

The understanding of nitric oxide (NO) signaling has grown substantially since the
identification of endothelial derived relaxing factor (EDRF). NO has emerged as a ubiquitous …

Nitric oxide (NO) is a key physiological mediator, and the association of disordered NO
generation with many pathological conditions has led to much interest in pharmacologically …

Nitric oxide (NO) exerts important protective actions on the cardiovascular system.
Generated from L-arginine by the action of endothelial (or type 3) nitric oxide synthase …

Pharmacological compounds that release nitric oxide (NO) have been useful tools for
evaluating the broad role of NO in physiology and therapeutics. NO deficiency has been …

Nitric oxide (NO) exerts a variety of biological actions under both physiological and
pathological conditions. NO is synthesized by three distinct NO synthase (NOS) isoforms …