MI Ryder - Journal of periodontology, 2020 - Wiley Online Library
Epidemiological studies have identified an association between periodontitis and Alzheimer disease (AD); however, the nature of this association has been unclear. Recent work …
U Haditsch, T Roth, L Rodriguez… - Journal of …, 2020 - content.iospress.com
Background: Porphyromonas gingivalis (P. gingivalis) and its gingipain virulence factors have been identified as pathogenic effectors in Alzheimer's disease (AD). In a recent study …
Porphyromonas gingivalis is a Gram-negative, rod-shaped, obligate anaerobe that obtains its metabolic energy from protein breakdown products, heme, and vitamin K for its growth. It …
S Kanagasingam, SS Chukkapalli… - Journal of …, 2020 - content.iospress.com
Porphyromonas gingivalis (P. gingivalis) is one of the several important bacterial pathogens associated with the sporadic Alzheimer's disease (AD). Different serotypes are either …
MI Ryder, P Xenoudi - Periodontology 2000, 2021 - Wiley Online Library
Loss of cognitive function in the aging population, particular those with Alzheimer disease, presents unique challenges to health practitioners. For the dental practitioner these include …
SK Singhrao, A Harding, S Poole… - Mediators of …, 2015 - Wiley Online Library
Periodontal disease (PD) and Alzheimer's disease (AD) are inflammatory conditions affecting the global adult population. In the pathogenesis of PD, subgingival complex …
SK Singhrao, I Olsen - Journal of oral microbiology, 2019 - Taylor & Francis
Chronic periodontitis of 10 years' duration is reported to become a twofold risk factor for the development of Alzheimer's disease (AD). Periodontitis is modifiable, and this fits with the …
A Elwishahy, K Antia, S Bhusari… - Journal of …, 2021 - content.iospress.com
Background: Alzheimer's disease (AD) is a chronic neurodegenerative disease that accounts for more than 50% of all dementia cases worldwide. There is wide consensus on …
Y Liu, Z Wu, Y Nakanishi, J Ni, Y Hayashi… - Scientific reports, 2017 - nature.com
Despite a clear correlation between periodontitis and cognitive decline in Alzheimer's disease, the precise mechanism underlying the relationship remains unclear. The …