Gut microbiome profiling of neonates using Nanopore MinION and Illumina MiSeq sequencing

T Cha, HH Kim, J Keum, MJ Kwak, JY Park… - Frontiers in …, 2023 - frontiersin.org
This study aimed to evaluate the difference in gut microbiomes between preterm and term
infants using third-generation long-read sequencing (Oxford Nanopore Technologies, ONT) …

Rapid MinION profiling of preterm microbiota and antimicrobial-resistant pathogens

RM Leggett, C Alcon-Giner, D Heavens, S Caim… - Nature …, 2020 - nature.com
The MinION sequencing platform offers near real-time analysis of DNA sequence; this
makes the tool attractive for deployment in fieldwork or clinical settings. We used the MinION …

Rapid profiling of the preterm infant gut microbiota using nanopore sequencing aids pathogen diagnostics

RM Leggett, C Alcon-Giner, D Heavens, S Caim… - bioRxiv, 2017 - biorxiv.org
ABSTRACT The Oxford Nanopore MinION sequencing platform offers direct analysis of DNA
reads as they are generated, which combined with its low cost, low power and extremely …

[PDF][PDF] Rapid MinION metagenomic profiling of the preterm infant gut microbiota to aid in pathogen diagnostics

RM Leggett, C Alcon-Giner, D Heavens, S Caim… - …, 2017 - pdfs.semanticscholar.org
ABSTRACT The Oxford Nanopore MinION sequencing platform offers direct analysis of DNA
reads as they are generated, which combined with its low cost, low power and extremely …

Metagenomics approaches to investigate the neonatal gut microbiome

Z Boudar, S Sehli, S El Janahi, N Al Idrissi… - Frontiers in …, 2022 - frontiersin.org
Early infancy is critical for the development of an infant's gut flora. Many factors can influence
microbiota development during the pre-and postnatal periods, including maternal factors …

The development of gut microbiota in critically ill extremely low birth weight infants assessed with 16S rRNA gene based sequencing

T Drell, I Lutsar, J Štšepetova, Ü Parm, T Metsvaht… - Gut …, 2014 - Taylor & Francis
Objective: An increasing number of studies that are using high-throughput molecular
methods are rapidly extending our knowledge of gut microbial colonization in preterm …

Methods for exploring the faecal microbiome of premature infants: a review

JAF Westaway, R Huerlimann, CM Miller… - … health, neonatology and …, 2021 - Springer
The premature infant gut microbiome plays an important part in infant health and
development, and recognition of the implications of microbial dysbiosis in premature infants …

Gut microbiome developmental patterns in early life of preterm infants: impacts of feeding and gender

X Cong, W Xu, S Janton, WA Henderson, A Matson… - PloS one, 2016 - journals.plos.org
Gut microbiota plays a key role in multiple aspects of human health and disease, particularly
in early life. Distortions of the gut microbiota have been found to correlate with fatal diseases …

Hospitalized premature infants are colonized by related bacterial strains with distinct proteomic profiles

CT Brown, W Xiong, MR Olm, BC Thomas, R Baker… - MBio, 2018 - Am Soc Microbiol
During the first weeks of life, microbial colonization of the gut impacts human immune
system maturation and other developmental processes. In premature infants, aberrant …

Strain-resolved analysis of hospital rooms and infants reveals overlap between the human and room microbiome

B Brooks, MR Olm, BA Firek, R Baker… - Nature …, 2017 - nature.com
Preterm infants exhibit different microbiome colonization patterns relative to full-term infants,
and it is speculated that the hospital room environment may contribute to infant microbiome …