Nano-Based Drug Delivery Systems: Potential Developments in the Therapy of Metastatic Osteosarcoma—A Narrative Review

Y Luo, M Sun, L Tan, T Li, L Min - Pharmaceutics, 2023 - mdpi.com
Osteosarcoma, a predominant malignant bone tumor, poses significant challenges due to its
high metastatic and recurrent nature. Although various therapeutic strategies are currently in …

[HTML][HTML] Recent advances of drug delivery nanocarriers in osteosarcoma treatment

SY Wang, HZ Hu, XC Qing, ZC Zhang… - Journal of Cancer, 2020 - ncbi.nlm.nih.gov
Osteosarcoma is the most common primary malignant bone tumor mainly occurred in
children and adolescence, and chemotherapy is limited for the side effects and development …

Nanosized drug delivery strategies in osteosarcoma chemotherapy

C Chen, S Wang, J Wang, F Yao, X Tang… - APL bioengineering, 2023 - pubs.aip.org
Despite recent developments worldwide in the therapeutic care of osteosarcoma (OS), the
ongoing challenges in overcoming limitations and side effects of chemotherapy drugs …

Nanocarrier-based drug delivery systems for bone cancer therapy: a review

SR Prasad, TSS Kumar, A Jayakrishnan - Biomedical Materials, 2021 - iopscience.iop.org
Bone cancer is a malignant tumor that originates in the bone and destroys the healthy bone
tissues. Of the various types of bone tumors, osteosarcoma is the most commonly diagnosed …

Advanced nanoparticles, the hallmark of targeted drug delivery for osteosarcoma-an updated review

S Ashique, M Faiyazuddin, O Afzal, S Gowri… - Journal of Drug Delivery …, 2023 - Elsevier
Osteosarcoma could be a sort of threatening tumor that starts in a bone and spreads to
adjoining bone cells. Among the different sorts of bone malignancies, osteosarcoma is the …

Active targeting schemes for nano-drug delivery systems in osteosarcoma therapeutics

P Shi, Z Cheng, K Zhao, Y Chen, A Zhang… - Journal of …, 2023 - Springer
Osteosarcoma, the most common malignant tumor of the bone, seriously influences people's
lives and increases their economic burden. Conventional chemotherapy drugs achieve …

Targeted nanomedicines for the treatment of bone disease and regeneration

F Ordikhani, N Zandi, M Mazaheri… - Medicinal Research …, 2021 - Wiley Online Library
Targeted delivery by either passive or active targeting of therapeutics to the bone is an
attractive treatment for various bone related diseases such as osteoporosis, osteosarcoma …

Nanodelivery systems face challenges and limitations in bone diseases management

F Giordano, S Lenna, R Rampado… - Advanced …, 2021 - Wiley Online Library
Bone is a highly dynamic tissue. Hence, diseases affecting bone tissue, such as cancer
(primary tumors and metastases), osteoporosis, and genetic conditions present many …

Drug delivery nanocarriers and recent advances ventured to improve therapeutic efficacy against osteosarcoma: an overview

SA Desai, A Manjappa, P Khulbe - Journal of the Egyptian National …, 2021 - Springer
Background Osteosarcoma (OS) is one of the key cancers affecting the bone tissues,
primarily occurred in children and adolescence. Recently, chemotherapy followed by …

Advanced nanoscale drug delivery systems for bone cancer therapy

N Amiryaghoubi, M Fathi, J Barar, H Omidian… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Bone tumors are relatively rare, which are complex cancers and primarily involve the long
bones and pelvis. Bone cancer is mainly categorized into osteosarcoma (OS) …