[HTML][HTML] The potential role of RNA modification in skin diseases, as well as the recent advances in its detection methods and therapeutic agents

Y Yu, C Liang, X Wang, Y Shi, L Shen - Biomedicine & Pharmacotherapy, 2023 - Elsevier
RNA modification is considered as an epigenetic modification that plays an indispensable
role in biological processes such as gene expression and genome editing without altering …

RNA modifications as emerging therapeutic targets

A Cayir - Wiley Interdisciplinary Reviews: RNA, 2022 - Wiley Online Library
The field of epitranscriptome, posttranscriptional modifications to RNAs, is still growing up
and has presented substantial evidences for the role of RNA modifications in diseases. In …

Detection, Clinical Application, and Manipulation of RNA Modifications

J Mo, X Weng, X Zhou - Accounts of Chemical Research, 2023 - ACS Publications
Conspectus With increasing research interest, more than 170 types of chemical
modifications of RNA have been characterized. The epigenetic modifications of RNA do not …

Targeting microRNA for improved skin health

X Li, S Ponandai‐Srinivasan… - Health Science …, 2021 - Wiley Online Library
Background In human skin, miRNAs have important regulatory roles and are involved in the
development, morphogenesis, and maintenance by influencing cell proliferation …

RNA A-to-I editing, environmental exposure, and human diseases

A Cayir - Critical Reviews in Toxicology, 2021 - Taylor & Francis
Epigenetic modifications have gained attention since they can be potentially changed with
environmental stimuli and can be associated with adverse health outcomes …

RNA modifications identification based on chemical reactions

Z Zhao, W Yan, X Weng - Bioorganic & Medicinal Chemistry, 2024 - Elsevier
RNA modification identification is an emerging field in epigenetics due to its indispensable
regulatory role in the cell life cycle. With advancements in identification methods, an …

[HTML][HTML] The molecular revolution in cutaneous biology: noncoding RNAs: new molecular players in dermatology and cutaneous biology

NV Botchkareva - Journal of Investigative Dermatology, 2017 - Elsevier
Progress in genome sequencing achieved during the last two decades revealed that only
about 2% of the genome codes for proteins, while the largest genome fraction is encoding …

RNA Modifications and Epitranscriptomics

C Yi, J Yang - Genomics, Proteomics & Bioinformatics, 2023 - academic.oup.com
More than 170 distinct chemical modifications have been identified in non-coding and
coding RNAs. Accumulating evidence suggests that RNA modifications play pivotal roles at …

RNA modifications: importance in immune cell biology and related diseases

L Cui, R Ma, J Cai, C Guo, Z Chen, L Yao… - Signal transduction and …, 2022 - nature.com
RNA modifications have become hot topics recently. By influencing RNA processes,
including generation, transportation, function, and metabolization, they act as critical …

Decreased A-to-I RNA editing as a source of keratinocytes' dsRNA in psoriasis

L Shallev, E Kopel, A Feiglin, GS Leichner, D Avni… - Rna, 2018 - rnajournal.cshlp.org
Recognition of dsRNA molecules activates the MDA5–MAVS pathway and plays a critical
role in stimulating type-I interferon responses in psoriasis. However, the source of the …