Interaction between N6-methyladenosine (m6A) modification and environmental chemical-induced diseases in various organ systems

X Zhu, H Fu, J Sun, Q Xu - Chemico-Biological Interactions, 2023 - Elsevier
A wide variety of chemicals are ubiquitous in the environment and thus exposure to these
environmental chemicals poses a serious threat to public health. Particularly, environmental …

The role of N6-methyladenosine methylation in environmental exposure-induced health damage

Y Feng, T Liu, S Xu, Y Ren, Y Ge, L Yin, Y Pu… - … Science and Pollution …, 2022 - Springer
The health risks caused by environmental pollution have long been of substantial concern.
With the development of epigenetics, a large number of studies have demonstrated that N6 …

Novel insights into the roles of RNA N6-methyladenosine modification in regulating gene expression during environmental exposures

D Li, X Zhu, Y Li, X Zeng - Chemosphere, 2020 - Elsevier
Abstract N 6-methyladenosine (m 6 A) is one of the most common RNA modifications in
eukaryotes involved in the regulation of post-transcriptional gene expression, as well as the …

Emerging roles of N6-methyladenosine (m6A) epitranscriptomics in toxicology

E Malovic, A Ealy, A Kanthasamy… - Toxicological …, 2021 - academic.oup.com
Epitranscriptomics, the study of chemically modified RNAs, is a burgeoning field being
explored in a variety of scientific disciplines. Of the currently known epitranscriptomic …

The role of N6-methyladenosine methylation in PAHs-induced cancers

Y Wei, X Guo, L Li, W Xue, L Wang, C Chen… - … Science and Pollution …, 2023 - Springer
Polycyclic aromatic hydrocarbons (PAHs), which are a wide range of environmental
toxicants, may act on humans through inhalation, ingestion, and skin contact, resulting in a …

[HTML][HTML] A narrative review of the role of m6A in oxidative stress and inflammation

Z Chen, X Chen, Y Ji, L Zhang, W Wang, Y Shen… - …, 2022 - biotarget.amegroups.org
Objective: To provide a comprehensive overview of the role and possible mechanism of N6-
methyladenosine (m6A) in oxidative stress and inflammation. Background: Oxidative stress …

[HTML][HTML] Integrated analysis of transcriptome-wide m6A methylation in a Cd-induced kidney injury rat model

S Li, H Zhou, Y Liang, Q Yang, J Zhang, W Shen… - Ecotoxicology and …, 2023 - Elsevier
Background Accumulating evidence has demonstrated that N6-methyladenosine (m 6 A)
plays important roles in a variety of diseases. However, the specific functions of m 6 A in …

[HTML][HTML] N6-methyladenosine RNA modification in inflammation: roles, mechanisms, and applications

J Luo, T Xu, K Sun - Frontiers in cell and developmental biology, 2021 - frontiersin.org
N6-methyladenosine (m6A) is the most prevalent internal mRNA modification. m6A can be
installed by the methyltransferase complex and removed by demethylases, which are …

The emerging role of N6-methyladenine RNA methylation in metal ion metabolism and metal-induced carcinogenesis

Y Liang, H Wang, B Wu, N Peng, D Yu, X Wu… - Environmental …, 2023 - Elsevier
Abstract N 6-methyladenine (m 6 A) is the most common and abundant internal modification
in eukaryotic mRNAs, which can regulate gene expression and perform important biological …

METTL3 regulates PM2. 5-induced cell injury by targeting OSGIN1 in human airway epithelial cells

Q Yuan, H Zhu, H Liu, M Wang, H Chu… - Journal of Hazardous …, 2021 - Elsevier
Abstract N 6-methyladenosine (m 6 A) is implicated in alteration of cellular biological
processes caused by exogenous environmental factors. However, little is known about the …