Gliomas differ from many other tumors as they grow infiltratively into the brain parenchyma
rather than forming a solid tumor mass with a well-defined boundary. Tumor cells can be …

Glioblastoma differ from many other tumors in the sense that they grow infiltratively into the
brain tissue instead of forming a solid tumor mass with a defined boundary. Only the part of …

Glioblastoma (GBM) is a highly invasive brain tumor, whose cells infiltrate surrounding
normal brain tissue beyond the lesion outlines visible in the current medical scans. These …

Glioblastoma multiforme (GBM) is the most malignant form of primary brain tumors known as
gliomas. They proliferate and invade extensively and yield short life expectancies despite …

Purpose To demonstrate a method of generating patient-specific, biologically-guided
radiotherapy dose plans and compare them to the standard-of-care protocol. Methods and …

Purpose: This study investigates the feasibility of personalizing radiotherapy prescription
schemes (treatment margins and fractional doses) for glioblastoma (GBM) patients and their …

Purpose: To estimate a plausible set of radiobiologic parameters such as α, α/β values, from
clinical outcomes for biologically based radiation treatment planning of brain tumors …

Background High grade gliomas (HGG) are typically treated with a combination of surgery,
radiotherapy and chemotherapy. Three dimensional (3D) conformal radiotherapy treatment …

In this article, we propose a proof of concept for the automatic planning of personalized
radiotherapy for brain tumors. A computational model of glioblastoma growth is combined …

Purpose: To evaluate the spatial relationship between peritumoral edema and recurrence
pattern in patients with glioblastoma (GBM). Methods and Materials: Forty-eight primary …