An overview on tumor treating fields (TTFields) technology as a new potential subsidiary biophysical treatment for COVID-19

AR Farmani, F Mahdavinezhad, C Scagnolari… - Drug Delivery and …, 2022 - Springer
COVID-19 pandemic situation has affected millions of people with tens of thousands of
deaths worldwide. Despite all efforts for finding drugs or vaccines, the key role for the …

Tumor Treating Fields (TTFields) demonstrate antiviral functions in vitro, and safety for application to COVID-19 patients in a pilot clinical study

A Abutbul, H Mumblat, Y Porat, N Friedman… - Frontiers in …, 2023 - frontiersin.org
Coronaviruses are the causative agents of several recent outbreaks, including the COVID-
19 pandemic. One therapeutic approach is blocking viral binding to the host receptor. As …

The schemes, mechanisms and molecular pathway changes of Tumor Treating Fields (TTFields) alone or in combination with radiotherapy and chemotherapy

G Tanzhu, L Chen, G Xiao, W Shi, H Peng… - Cell Death …, 2022 - nature.com
Abstract Tumor Treating Fields (TTFields) is a physical therapy that uses moderate
frequency (100–300 kHz) and low-intensity (1–3 V/cm) alternating electric fields to inhibit …

[HTML][HTML] The therapeutic effects of tumor treating fields on cancer and noncancerous cells

EO Mahgoub, A Hussain, M Sharifi, M Falahati… - Arabian Journal of …, 2021 - Elsevier
Tumor treating fields (TTFields) are among clinically active anticancer modalities that utilize
low‐intensity, intermediate frequency (IF), and alternating electric fields (AEFs) to selectively …

Tumor treating fields: a comprehensive overview of the underlying molecular mechanism

P Hong, N Kudulaiti, S Wu, J Nie… - Expert review of …, 2022 - Taylor & Francis
Introduction As a novel treatment modality, tumor treating fields (TTFields) exert low-
intensity, medium-frequency electric fields on tumor cells. TTFields' effectiveness and safety …

Thymidine decreases the DNA damage and apoptosis caused by tumor‐treating fields in cancer cell lines

H Jeong, Y Jo, M Yoon, S Hong - Genes & Genomics, 2021 - Springer
Abstract Background Tumor-treating fields (TTFields) is an emerging non-invasive cancer-
treatment modality using alternating electric fields with low intensities and an intermediate …

Tumor-treating fields: a fourth modality in cancer treatment

EJ Mun, HM Babiker, U Weinberg, ED Kirson… - Clinical Cancer …, 2018 - AACR
Despite major advances in therapy, cancer continues to be a leading cause of mortality. In
addition, toxicities of traditional therapies pose a significant challenge to tolerability and …

Alternating electric fields (TTFields) induce immunogenic cell death resulting in enhanced antitumor efficacy when combined with anti-PD-1 therapy

M Giladi, T Voloshin, A Shteingauz… - The Journal of …, 2016 - journals.aai.org
Abstract Tumor Treating Fields (TTFields) are an effective anti-neoplastic treatment modality
delivered via noninvasive application of low intensity, intermediate frequency, alternating …

Tumor treating fields: at the crossroads between physics and biology for cancer treatment

FA Carrieri, C Smack, I Siddiqui, LR Kleinberg… - Frontiers in …, 2020 - frontiersin.org
Despite extraordinary advances that have been achieved in the last few decades, cancer
continues to represent a leading cause of mortality worldwide. Lethal cancer types ultimately …

Effect of duty cycles of tumor‑treating fields on glioblastoma cells and normal brain organoids Corrigendum in/10.3892/ijo. 2022.5397

E Ye, JE Lee, YS Lim, SH Yang… - … journal of oncology, 2022 - spandidos-publications.com
Tumor‑treating fields (TTFields) are emerging cancer therapies based on alternating low‑
intensity electric fields that interfere with dividing cells and induce cancer cell apoptosis …