Vaccination with proteins involved in tick–pathogen interactions reduces vector infestations and pathogen infection

O Merino, S Antunes, J Mosqueda, JA Moreno-Cid… - Vaccine, 2013 - Elsevier
Tick-borne pathogens cause diseases that greatly impact animal health and production
worldwide. The ultimate goal of tick vaccines is to protect against tick-borne diseases …

Targeting the tick protective antigen subolesin reduces vector infestations and pathogen infection by Anaplasma marginale and Babesia bigemina

O Merino, C Almazán, M Canales, M Villar… - Vaccine, 2011 - Elsevier
The ultimate goal of vector vaccines is the control of vector infestations while reducing
pathogen infection and transmission to protect against the many diseases caused by vector …

Control of tick infestations and pathogen prevalence in cattle and sheep farms vaccinated with the recombinant Subolesin-Major Surface Protein 1a chimeric antigen

A Torina, JA Moreno-Cid, V Blanda… - Parasites & vectors, 2014 - Springer
Background Despite the use of chemical acaricides, tick infestations continue to affect
animal health and production worldwide. Tick vaccines have been proposed as a cost …

Control of Rhipicephalus (Boophilus) microplus infestations by the combination of subolesin vaccination and tick autocidal control after subolesin gene knockdown in …

O Merino, C Almazán, M Canales, M Villar… - Vaccine, 2011 - Elsevier
Tick subolesin was shown in immunization trials using the recombinant protein to protect
hosts against tick infestations. In this study, we demonstrated that subolesin vaccination and …

Tick vaccines and the control of tick-borne pathogens

O Merino, P Alberdi, JM Pérez de la Lastra… - Frontiers in cellular …, 2013 - frontiersin.org
Ticks are obligate hematophagous ectoparasites that transmit a wide variety of pathogens to
humans and animals. The incidence of tick-borne diseases has increased worldwide in both …

Understanding tick biology and its implications in anti-tick and transmission blocking vaccines against tick-borne pathogens

B Bhowmick, Q Han - Frontiers in Veterinary Science, 2020 - frontiersin.org
Ticks are obligate blood-feeding ectoparasites that transmit a wide variety of pathogens to
animals and humans in many parts of the world. Currently, tick control methods primarily rely …

Protective efficacy of the peptide Subolesin antigen against the cattle tick Rhipicephalus microplus under natural infestation

N Mendoza-Martínez, MA Alonso-Díaz, O Merino… - Veterinary …, 2021 - Elsevier
The cattle tick Rhipicephalus microplus affect animal health, welfare, and cattle production in
tropical and subtropical zones of the world. Anti-tick vaccines have been an effective …

Oral Vaccination With a Formulation Combining Rhipicephalus microplus Subolesin With Heat Inactivated Mycobacterium bovis Reduces Tick Infestations in Cattle

M Contreras, PD Kasaija, O Merino… - Frontiers in Cellular …, 2019 - frontiersin.org
Vaccines are an environmentally friendly alternative to acaracides for the control of tick
infestations, to reduce the risk for tick-borne diseases affecting human and animal health …

Targeting a global health problem: Vaccine design and challenges for the control of tick-borne diseases

J de La Fuente, M Contreras, A Estrada-Peña… - Vaccine, 2017 - Elsevier
It has been over twenty years since the first vaccines for the control of tick infestations
became commercially available. These vaccines proved their efficacy and the potential of …

Identification and characterization of Rhipicephalus (Boophilus) microplus candidate protective antigens for the control of cattle tick infestations

C Almazán, R Lagunes, M Villar, M Canales… - Parasitology …, 2010 - Springer
Abstract The cattle ticks, Rhipicephalus (Boophilus) spp., affect cattle production in tropical
and subtropical regions of the world. Tick vaccines constitute a cost-effective and …