[HTML][HTML] Food-derived non-phenolic α-amylase and α-glucosidase inhibitors for controlling starch digestion rate and guiding diabetes-friendly recipes

X Li, Y Bai, Z Jin, B Svensson - Lwt, 2022 - Elsevier
Diabetes is considered one of the biggest health crises in 21st century. Controlling
carbohydrate digestibility by inhibiting starch digestive enzyme (α-amylase and α …

Functional significance and structure–activity relationship of food-derived α-glucosidase inhibitors

E Di Stefano, T Oliviero, CC Udenigwe - Current Opinion in Food Science, 2018 - Elsevier
Highlights•α-Glucosidase inhibition can reduce the rate of glucose release from ingested
carbohydrate.•Food phenolics, peptides, terpenoids and non-starch polysaccharides inhibit …

New insights into the latest advancement in α-amylase inhibitors of plant origin with anti-diabetic effects

H Kashtoh, KH Baek - Plants, 2023 - mdpi.com
The rising predominance of type 2 diabetes, combined with the poor medical effects seen
with commercially available anti-diabetic medications, has motivated the development of …

Dietary polyphenols as natural inhibitors of α-amylase and α-glucosidase

I Ćorković, D Gašo-Sokač, A Pichler, J Šimunović… - Life, 2022 - mdpi.com
It is well known that carbohydrates are the main source of calories in most diets. However,
by inhibiting carbohydrases, intake of calories is reduced and weight loss is improved. α …

Inhibitory potential of wine and tea against α‐amylase and α‐glucosidase for management of hyperglycemia linked to type 2 diabetes

YIN KWON, E Apostolidis… - Journal of Food …, 2008 - Wiley Online Library
Natural α‐amylase and α‐glucosidase inhibitors from food‐grade plants offer an attractive
strategy to manage postprandial hyperglycemia for type 2 diabetes management via control …

Inhibitors of α‐amylase and α‐glucosidase: Potential linkage for whole cereal foods on prevention of hyperglycemia

L Gong, D Feng, T Wang, Y Ren, Y Liu… - Food science & …, 2020 - Wiley Online Library
The strategy of reducing carbohydrate digestibility by controlling the activity of two
hydrolyzing enzymes (α‐amylase and α‐glucosidase) to control postprandial hyperglycemia …

Natural products for glycaemic control: Polyphenols as inhibitors of alpha-amylase

L Sun, FJ Warren, MJ Gidley - Trends in Food Science & Technology, 2019 - Elsevier
Background α-Amylase plays an important role in starch digestion, the main source of
exogenous glucose in the human diet. Retarding glucose absorption through delaying …

Structural requirements of flavonoids for the selective inhibition of α-amylase versus α-glucosidase

J Lim, MG Ferruzzi, BR Hamaker - Food Chemistry, 2022 - Elsevier
In the present study, 14 structurally unique flavonoids were screened to systematically
investigate structural requirements for selectively inhibiting human α-amylase versus α …

Inhibition of α-amylase by polyphenolic compounds: Substrate digestion, binding interactions and nutritional intervention

L Sun, Y Wang, M Miao - Trends in Food Science & Technology, 2020 - Elsevier
Background α-Amylase is a key enzyme of starch digestion, playing an important role in
deciding glucose releasing amount. Inhibition of the enzyme activity by polyphenols is …

Dietary phenolic compounds selectively inhibit the individual subunits of maltase-glucoamylase and sucrase-isomaltase with the potential of modulating glucose …

M Simsek, R Quezada-Calvillo… - Journal of agricultural …, 2015 - ACS Publications
In this study, it was hypothesized that dietary phenolic compounds selectively inhibit the
individual C-and N-terminal (Ct, Nt) subunits of the two small intestinal α-glucosidases …